| Registro completo |
| Provedor de dados: |
Biological Sciences
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| País: |
Brazil
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| Título: |
In vitro enzyme activity and in vivo healing activity of the protein extract from pineapple peel
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| Autores: |
Rocha, Denise Alvarenga
Queiroz, Estela de Rezende
Botelho, Lucimara Nazaré Silva
Fráguas, Rodrigo Martins
Santos, Cláudia Mendes dos
Abreu, Celeste Maria Patto
Sousa, Raimundo Vicente de
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| Data: |
2019-04-16
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| Ano: |
2019
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| Palavras-chave: |
Ciências Biológicas bromelain
Skin lesion
Enzyme activity
Pineapple and healing. Bioquímica
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| Resumo: |
The pineapple is a fruit that has wide acceptance worldwide both in natural form, as industrialized. Your peel is a residue generated by food industries and from this residue can obtain a protein extract which is a good source of bromelain. This study aimed to obtain a protein extract from pineapple peel, evaluate its enzyme activity and its healing properties in skin lesions in rats. Seven animal groups were used: control, treated with 5% of protein extract, 10% of protein extract and pure protein extract; 5% of commercial bromelain, 10% of commercial bromelain and pure commercial bromelain. The animals were subjected to a tissue incision and treated for 21 days. Proteolytic and specific activities of the protein extract were 1.30 U mg-1 and 45 x 10-3 U µg-1 and, for commercial bromelain, 1.04 U mg-1 and 6 x 10-3 U µg-1, respectively. In the histology of the lesion, there was no significant difference between the control and treated groups; however, macroscopically, the prepared topical formulations assisted in the recovery of skin lesions, providing a significant reduction in their width, in the groups treated with pure protein extract, 5 and 10% commercial bromelain, and pure bromelain.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/41466
10.4025/actascibiolsci.v41i1.41466
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| Editor: |
Universidade Estadual De Maringá
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| Relação: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/41466/pdf
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/downloadSuppFile/41466/17109
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/downloadSuppFile/41466/17110
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| Formato: |
application/pdf
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| Fonte: |
Acta Scientiarum. Biological Sciences; v. 41 (2019): Publicação contínua; e41466
Acta Scientiarum. Biological Sciences; v. 41 (2019): Publicação contínua; e41466
1807-863X
1679-9283
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| Direitos: |
Direitos autorais 2019 Acta Scientiarum. Biological Sciences
http://creativecommons.org/licenses/by/4.0
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