| Registro completo |
| Provedor de dados: |
Anais da ABC (AABC)
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| País: |
Brazil
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| Título: |
Impact of continuous flow chemistry in the synthesis of natural products and active pharmaceutical ingredients
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| Autores: |
SOUZA,JULIANA M. DE
GALAVERNA,RENAN
SOUZA,ALINE A.N. DE
BROCKSOM,TIMOTHY J.
PASTRE,JULIO C.
SOUZA,RODRIGO O.M.A. DE
OLIVEIRA,KLEBER T. DE
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| Data: |
2018-01-01
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| Ano: |
2018
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| Palavras-chave: |
Continuous flow
Natural products
APIs
Synthesis
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| Resumo: |
ABSTRACT We present a comprehensive review of the advent and impact of continuous flow chemistry with regard to the synthesis of natural products and drugs, important pharmaceutical products and definitely responsible for a revolution in modern healthcare. We detail the beginnings of modern drugs and the large scale batch mode of production, both chemical and microbiological. The introduction of modern continuous flow chemistry is then presented, both as a technological tool for enabling organic chemistry, and as a fundamental research endeavor. This part details the syntheses of bioactive natural products and commercial drugs.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000301131
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| Editor: |
Academia Brasileira de Ciências
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| Relação: |
10.1590/0001-3765201820170778
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| Formato: |
text/html
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| Fonte: |
Anais da Academia Brasileira de Ciências v.90 n.1 suppl.2 2018
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| Direitos: |
info:eu-repo/semantics/openAccess
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