Registro completo |
Provedor de dados: |
Anais da ABC (AABC)
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País: |
Brazil
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Título: |
Optimal condition of cannabis maceration to obtain the high cannabidiol and Δ9-tetrahydrocannabinol content
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Autores: |
MONTON,CHAOWALIT
MADAKA,FAMEERA
SETTHARAKSA,SUKANYA
WUNNAKUP,THANIYA
SUKSAEREE,JIRAPORNCHAI
SONGSAK,THANAPAT
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Data: |
2019-01-01
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Ano: |
2019
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Palavras-chave: |
Cannabis sativa
Cannabidiol
Δ9-tetrahydrocannabinol
Optimization
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Resumo: |
Abstract: The aim of this work was to optimize a maceration condition of cannabis (Cannabis sativa L.). A circumscribed central composite experimental design was applied in this work. Temperature and time were varied from 40-80 °C and 30-90 min, respectively. The three responses (i.e., extraction yield, cannabidiol content, and Δ9- tetrahydrocannabinol content) were predicted by computer software. The yield was high when cannabis was macerated using ethanol at high temperature and long duration time. While cannabidiol and Δ9- tetrahydrocannabinol content was high when macerating at a low heating temperature and short duration time. The optimal condition provided the simultaneous high of cannabidiol and Δ9- tetrahydrocannabinol content was 40 °C for 30 min. The prediction was accurate due to low percent error. This optimal condition could be used as a guide for maceration of cannabis to obtain the extract containing a high content of cannabidiol and Δ9- tetrahydrocannabinol.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500809
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Editor: |
Academia Brasileira de Ciências
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Relação: |
10.1590/0001-3765201920190676
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Formato: |
text/html
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Fonte: |
Anais da Academia Brasileira de Ciências v.91 n.3 2019
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Direitos: |
info:eu-repo/semantics/openAccess
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