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Provedor de dados:  Anais da ABC (AABC)
País:  Brazil
Título:  Optimal condition of cannabis maceration to obtain the high cannabidiol and Δ9-tetrahydrocannabinol content
Autores:  MONTON,CHAOWALIT
MADAKA,FAMEERA
SETTHARAKSA,SUKANYA
WUNNAKUP,THANIYA
SUKSAEREE,JIRAPORNCHAI
SONGSAK,THANAPAT
Data:  2019-01-01
Ano:  2019
Palavras-chave:  Cannabis sativa
Cannabidiol
Δ9-tetrahydrocannabinol
Optimization
Resumo:  Abstract: The aim of this work was to optimize a maceration condition of cannabis (Cannabis sativa L.). A circumscribed central composite experimental design was applied in this work. Temperature and time were varied from 40-80 °C and 30-90 min, respectively. The three responses (i.e., extraction yield, cannabidiol content, and Δ9- tetrahydrocannabinol content) were predicted by computer software. The yield was high when cannabis was macerated using ethanol at high temperature and long duration time. While cannabidiol and Δ9- tetrahydrocannabinol content was high when macerating at a low heating temperature and short duration time. The optimal condition provided the simultaneous high of cannabidiol and Δ9- tetrahydrocannabinol content was 40 °C for 30 min. The prediction was accurate due to low percent error. This optimal condition could be used as a guide for maceration of cannabis to obtain the extract containing a high content of cannabidiol and Δ9- tetrahydrocannabinol.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500809
Editor:  Academia Brasileira de Ciências
Relação:  10.1590/0001-3765201920190676
Formato:  text/html
Fonte:  Anais da Academia Brasileira de Ciências v.91 n.3 2019
Direitos:  info:eu-repo/semantics/openAccess
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