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Provedor de dados:  Anais da ABC (AABC)
País:  Brazil
Título:  Nasal carriage of resistant Staphylococcus aureus in a medical student community
Autores:  GUSHIKEN,CAROLINA Y.
MEDEIROS,LILIANE B.
CORREIA,BRUNA P.
SOUZA,JOYCE M.
MORIS,DANIELA V.
PEREIRA,VALERIA C.
GIUFFRIDA,ROGERIO
RODRIGUES,MARCUS V.P.
Data:  2016-09-01
Ano:  2016
Palavras-chave:  Multidrug resistance
Colonization
MLSB resistance
MRSA
Resumo:  ABSTRACT Staphylococcus aureus can cause a variety of infections due to its high transmissibility, high pathogenic potential and resistance to multiple drugs, factors that contribute to the relevance of infections in healthcare services. The aim of this study was to document phenotypic and genotypic resistance factors of Staphylococcus aureus strains, isolated from nasal mucosa of medical students. A nasal swab was collected from the nares (nostrils) of 222 medical students. After collection, the samples were submitted to isolation and identification procedures. From 204 valid samples, 20.6% (42 samples) were positive for S. aureus. For the assessment of phenotypic resistance by disk-diffusion technique, from 42 samples, 95.2% showed resistance to erythromycin, 42.8% to clindamycin, 16.6% to cephoxitin and 9.5% to oxacillin. The D test showed that 26.2% of samples were resistant to macrolides, lincosamides and streptogramin B. A PCR assay allowed for the evaluation of a genotypic resistance profile, in which 16.6% of the samples were positive for the mecA gene, 35.7% positive for the ermC gene or ermA gene and 28.5% were positive for both genes. These results demonstrate that medical students can enter the healthcare service previously colonized by multidrug resistant strains and become potential spreaders in the hospital environment.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401501
Editor:  Academia Brasileira de Ciências
Relação:  10.1590/0001-3765201620160123
Formato:  text/html
Fonte:  Anais da Academia Brasileira de Ciências v.88 n.3 2016
Direitos:  info:eu-repo/semantics/openAccess
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