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Provedor de dados:  Anais da ABC (AABC)
País:  Brazil
Título:  Effects of electroacupuncture on stress and anxiety-related responses in rats
Autores:  BASSETTO,RICARDO M.
WSCIEKLICA,TATIANA
POUZA,KATHLEIN C.P.
ORTOLANI,DANIELA
VIANA,MILENA B.
CESPEDES,ISABEL C.
SPADARI,REGINA C.
Data:  2017-06-01
Ano:  2017
Palavras-chave:  Stress
Electroacupuncture
Anxiety
Elevated plus-maze
Fos-immunoreactivity
Resumo:  ABSTRACT The aim of this work was to investigate if eletroacupuncture at PC6 would modulate the stress-induced anxiety-like behavior and the level of activation of several brain areas. Rats were distributed in groups: control; submitted to immobilization; submitted to immobilization and eletroacupuncture at PC6 or at the tail. Immobilization increased grooming and decreased stretched attend postures and the time spent in the open arms of the ele-vated plus-maze. Eletroacupuncture at PC6 or tail canceled the effect of immobilization on grooming and attenuated the stretched attend posture. Immobilization increased Fos-immunoreactivity in the prefrontal cortex, medial and central amygdala, paraventricular and dorsomedial nuclei of the hypothalamus, lateral hypothalamus, dentate gyrus, CA1, CA2 and CA3 hippocampal areas. The activation of paraventricular, dorsomedial nuclei and prefrontal cortex by immobilization was canceled by electroacupuncture at PC6 and attenuated by electroacupuncture in the tail. The activation of the other areas was canceled by electroacupuncture in PC6 or the tail. It is concluded that immobilization induced anxiety-like behavior that was moderately attenuated by eletroacupuncture with difference between the stimulation in PC6 or the rat tail. Eletroacupuncture showed specificity concerning to the attenuation of the effects of immobilization in the CNS areas related to the stress response, anxiety and cardiovascular system.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000301003
Editor:  Academia Brasileira de Ciências
Relação:  10.1590/0001-3765201720160531
Formato:  text/html
Fonte:  Anais da Academia Brasileira de Ciências v.89 n.2 2017
Direitos:  info:eu-repo/semantics/openAccess
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