| Registro completo |
| Provedor de dados: |
Arq. Bras. Med. Vet. Zootec.
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| País: |
Brazil
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| Título: |
Mielograma de ratas com disfunção tireoidiana
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| Autores: |
Castro,R.D
Silva,J.F
Ocarino,N.M
Boeloni,J.N
Nunes,P.P
Silva,G.R
Melo,M.M
Paes,P.R.O
Serakides,R
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| Data: |
2011-10-01
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| Ano: |
2011
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| Palavras-chave: |
Rata
Mielograma
Hipotiroidismo
Hipertireoidismo
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| Resumo: |
The cells of the myelo id, lymphoid , and erythroid lineage s of the bone marrow were quantified in rats with hypo and hyperthyroidism. Fifteen Wistar rats were divided into three groups: hypothyroid (n=5), hyperthyroid (n=5) , and control (n=5). Three months after the onset of the treatment s, euthanasia was performed . Bone marrow was aspirated from femurs of each animal to perform smear s that were stained with Quick Panoptic. T he percentage s of rubroblast, prorubrocyte, metarubrocyte, myeloblast, promyelocytes, metamyelocytes, myel ocytes, segmented, eosinophils, basophils, lymphocytes, plasma cells and monocytes in were determined a total of 500 cells. The bone marrow of animals with hypothyroidism had hypoplasia. The myeloid:erythroid ratio was higher in animals with thyroid dysfun ction. In hypo and hyperthyroidism, there was a significant reduction of the percentage of rubrocyte, metarubrocyte , and lymphocytes and increase of myelocytes and segmented cells. In hypothyroidism, there was a significant increase in the percentage of me tamyelocytes. It is c oncluded that both hypo and hyperfunction of thyroid increase the myeloid:erythroid ratio by increasing the number of cells of the myeloid lineage and reducing the cells of the erythroid lineage.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Português
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000500030
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| Editor: |
Universidade Federal de Minas Gerais, Escola de Veterinária
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| Relação: |
10.1590/S0102-09352011000500030
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| Formato: |
text/html
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| Fonte: |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.63 n.5 2011
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| Direitos: |
info:eu-repo/semantics/openAccess
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