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Provedor de dados:  Biocell
País:  Argentina
Título:  Probiotics enhance the recovery of gut atrophy in experimental malnutrition
Autores:  Dock,Diana B.
Aguilar-Nascimento,José E.
Latorraca,Marcia Q.
Data:  2004-08-01
Ano:  2004
Palavras-chave:  Probiotics
Malnutrition
Small bowel
Colon
Mucosa
Resumo:  AIM: The aim of this study was to evaluate the effect of probiotics on the recovery of the bowel atrophy induced by malnutrition in rats. METHODS: Twenty-and-six Wistar rats (200-250g) were fed with either a normoproteic (sham group, n=6) or a free-protein diet (n=20) during 12 days. Twelve malnourished rats were randomized to recover during 15 days with either a hydrolyzed diet (control group, n=6) or the same diet enriched with probiotics (Streptococcus thermophilus and Lactobacillus helveticus; probiotic group, n=6). RESULTS: Probiotic group showed similar gain of body, liver and bowel weight than controls. At the jejunum, both the villus height (383±49 vs. 321±46mm; p=0.04) and crypt depth (157±31 vs. 125±10mm; p=0.04) were greater in probiotic group than in controls. The crypt depth at the cecum (214±22 vs. 169±43 mm; p=0.05) and the wall width at both the cecum (410±18 vs. 340±61 mm; p=0.02) and sigmoid (479±130 vs. 330±62 mm; p=0.03) were higher in probiotic than in control group. CONCLUSION: Streptococcus thermophilus and Lactobacillus helveticus enhance the recovery of gut atrophy induced by malnutrition. Probiotics can be useful as oral adjuvants during the recovery of malnutrition.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452004000200003
Editor:  Sociedad Latinoamericana de Microscopía Electrónica.; Centro Regional de Investigaciones Científicas y Tecnológicas (Mendoza, Argentina)
Formato:  text/html
Fonte:  Biocell v.28 n.2 2004
Direitos:  info:eu-repo/semantics/openAccess
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