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Provedor de dados:  Biol. Res.
País:  Chile
Título:  Ethanol Intake during Lactation Alters Milk Nutrient Composition and Growth and Mineral Status of Rat Pups
Autores:  AZARA,CÍNTIA R.P
MAIA,INGRID C
RANGEL,CAROLINA N
SILVA-NETO,MÁRIO A.C
SERPA,RENATA F.B
DE JESUS,EDGAR F.O
TAVARES  DO CARMO,MARIA G
FIALHO,ELIANE
Data:  2008-01-01
Ano:  2008
Palavras-chave:  Breast milk
Ethanol
Rats
Lactation
Minerals status and milk composition
Resumo:  Lactating Wistar rats were fed a liquid diet containing either ethanol [ethanol-fed group (EFG)] or an isocaloric amount of carbohydrate [pair-fed group (PFG)] from day 1 postpartum up to day 14 of lactation, to investigate micro/macronutrient milk composition and the mineral status of pups. EFG presented a reduction of daily milk production and milk composition was significantly higher in protein and lower in carbohydrate, while the lipid content was similar to that of PFG. When compared to PFG, the milk of EFG had a decreased proportion of C22:6 n-3 fatty acid and an increase in medium-chain fatty acids and of several minerals. Pups of EFG showed reduced growth and a lower concentration of Cu and Sr in plasma and lower concentrations of Ca, P and Cl, and higher concentrations of Cd in the brain. We conclude that maternal EtOH intake greatly impairs lactational performance and modifies the mineral status of pups.
Tipo:  Journal article
Idioma:  Inglês
Identificador:  http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000300008
Editor:  Sociedad de Biología de Chile
Formato:  text/html
Fonte:  Biological Research v.41 n.3 2008
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