| Registro completo |
| Provedor de dados: |
ArchiMer
|
| País: |
France
|
| Título: |
Quorum Sensing Inhibitory and Antifouling Activities of New Bromotyrosine Metabolites from the Polynesian Sponge Pseudoceratina n. sp.
|
| Autores: |
Tintillier, Florent
Moriou, Céline
Petek, Sylvain
Fauchon, Marilyne
Hellio, Claire
Saulnier, Denis
Ekins, Merrick
Hooper, John N. A.
Al-mourabit, Ali
Debitus, Cecile
|
| Data: |
2020-05
|
| Ano: |
2020
|
| Palavras-chave: |
Sponge
Pseudoceratina
Quorum sensing inhibitory activity
Antifouling
Verongiida
Bromotyrosine
|
| Resumo: |
Four new brominated tyrosine metabolites, aplyzanzines C–F (1–4), were isolated from the French Polynesian sponge Pseudoceratina n. sp., along with the two known 2-aminoimidazolic derivatives, purealidin A (5) and 6, previously isolated, respectively, from the sponges Psammaplysilla purpurea and Verongula sp. Their structures were assigned based on the interpretation of their NMR and HRMS data. The compounds exhibited quorum sensing inhibition (QSi) and antifouling activities against several strains of bacteria and microalgae. To our knowledge, the QSi activity of this type of bromotyrosine metabolite is described here for the first time.
|
| Tipo: |
Text
|
| Idioma: |
Inglês
|
| Identificador: |
https://archimer.ifremer.fr/doc/00630/74200/73825.pdf
https://archimer.ifremer.fr/doc/00630/74200/73826.pdf
DOI:10.3390/md18050272
https://archimer.ifremer.fr/doc/00630/74200/
|
| Editor: |
MDPI AG
|
| Formato: |
application/pdf
|
| Fonte: |
Marine Drugs (1660-3397) (MDPI AG), 2020-05 , Vol. 18 , N. 5 , P. 272 (17p.)
|
| Direitos: |
info:eu-repo/semantics/openAccess
restricted use
|
|
