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Provedor de dados:  ArchiMer
País:  France
Título:  PenBase, the shrimp antimicrobial peptide penaeidin database: Sequence-based classification and recommended nomenclature
Autores:  Gueguen, Yannick
Garnier, Julien
Robert, Lorenne
Lefranc, Marie-paule
Mougenot, Isabelle
De Lorgeril, Julien
Janech, Michael
Gross, Paul S.
Warr, Gregory W.
Cuthbertson, Brandon
Barracco, Margherita A.
Bulet, Philippe
Aumelas, André
Yang, Yinshan
Bo, Dong
Xiang, Jianhai
Tassanakajon, Anchalee
Piquemal, Piquemal
Bachere, Evelyne
Data:  2006
Ano:  2006
Palavras-chave:  Nomenclature
Sequence database
Antimicrobial peptide
Penaeid shrimp
Resumo:  Antimicrobial peptides play a major role in innate immunity. The penaeidins, initially characterized from the shrimp Litopenaeus vannamei, are a family of antimicrobial peptides that appear to be expressed in all penaeid shrimps. As of recent, a large number of penaeid nucleotide sequences have been identified from a variety of penaeid shrimp species and these sequences currently reside in several databases under unique identifiers with no nomenclatural continuity. To facilitate research in this field and avoid potential confusion due to a diverse number of nomenclatural designations, we have made a systematic effort to collect, analyse, and classify all the penaeidin sequences available in every database. We have identified a common penaeidin signature and subsequently established a classification based on amino acid sequences. In order to clarify the naming process, we have introduced a 'penaeidin nomenclature' that can be applied to all extant and future penaeidins. A specialized database, PenBase, which is freely available at, has been developed for the penaeidin family of antimicrobial peptides, to provide comprehensive information about their properties, diversity and nomenclature. (c) 2005 Elsevier Ltd. All rights reserved.
Tipo:  Text
Idioma:  Inglês

Editor:  Elsevier
Formato:  application/pdf
Fonte:  Developmental & Comparative Immunology (0145-305X) (Elsevier), 2006 , Vol. 30 , N. 3 , P. 283-288
Direitos:  2005 Elsevier Ltd All rights reserved

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