| Registro completo |
| Provedor de dados: |
ArchiMer
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| País: |
France
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| Título: |
The Complete Genome Sequence of the Fish Pathogen Tenacibaculum maritimum Provides Insights into Virulence Mechanisms
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| Autores: |
Perez-pascual, David
Lunazzi, Aurelie
Magdelenat, Ghislaine
Rouy, Zoe
Roulet, Alain
Lopez-roques, Celine
Larocque, Robert
Barbeyron, Tristan
Gobet, Angelique
Michel, Gurvan
Bernardet, Jean-francois
Duchaud, Eric
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| Data: |
2017-08
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| Ano: |
2017
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| Palavras-chave: |
Tenacibaculum maritimum
Fish pathogen
Virulence factors
Genome
Toxins
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| Resumo: |
Tenacibaculum maritimum is a devastating bacterial pathogen of wild and farmed marine fish with a broad host range and a worldwide distribution. We report here the complete genome sequence of the T. maritimum type strain NCIMB 2154(T). The genome consists of a 3,435,971-base pair circular chromosome with 2,866 predicted protein-coding genes. Genes encoding the biosynthesis of exopolysaccharides, the type IX secretion system, iron uptake systems, adhesins, hemolysins, proteases, and glycoside hydrolases were identified. They are likely involved in the virulence process including immune escape, invasion, colonization, destruction of host tissues, and nutrient scavenging. Among the predicted virulence factors, type IX secretion-mediated and cell-surface exposed proteins were identified including an atypical sialidase, a sphingomyelinase and a chondroitin AC lyase which activities were demonstrated in vitro.
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| Tipo: |
Text
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| Idioma: |
Inglês
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| Identificador: |
https://archimer.ifremer.fr/doc/00488/59939/63150.pdf
https://archimer.ifremer.fr/doc/00488/59939/63151.pdf
https://archimer.ifremer.fr/doc/00488/59939/63152.pdf
https://archimer.ifremer.fr/doc/00488/59939/63153.pdf
https://archimer.ifremer.fr/doc/00488/59939/63154.pdf
https://archimer.ifremer.fr/doc/00488/59939/63155.pdf
https://archimer.ifremer.fr/doc/00488/59939/63156.pdf
https://archimer.ifremer.fr/doc/00488/59939/63157.pdf
DOI:10.3389/fmicb.2017.01542
https://archimer.ifremer.fr/doc/00488/59939/
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| Editor: |
Frontiers Media Sa
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| Formato: |
application/pdf
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| Fonte: |
Frontiers In Microbiology (1664-302X) (Frontiers Media Sa), 2017-08 , Vol. 8 , N. 1542 , P. 11p.
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| Direitos: |
info:eu-repo/semantics/openAccess
restricted use
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