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Provedor de dados:  BABT
País:  Brazil
Título:  Current evaluation of the clinical utility of Fluoromethylcholine-(18F) PET/CT in Prostate Cancer
Autores:  Talbot,Jean-Nöel
Chevalme,Yanna-Marina
Data:  2008-12-01
Ano:  2008
Palavras-chave:  Fluoromethylcholine-(18F)
PET/CT
Prostate cancer
Evaluation of radiopharmaceuticals
Resumo:  This short review is dedicated to the current status of the assessment of a new PET radiopharmaceutical, fluoromethylcholine-(18F) or FCH, which is taken-up by prostate cancer tissue, in contrary to fluorodeoxyglucose-(18F) or FDG. It seems that FCH could become "the FDG of prostate cancer", with the same type of achievements (detection of distant metastases and of occult recurrences, restaging prior to invasive treatments), and the same drawbacks (false negative results in case of small lesions, in particular lymph nodes metastases, and false positive results in case of infection/inflammation, in particular prostatitis). Current evidence is summarised and discussed for each of the potential settings of FCH PET/CT imaging in prostate cancer. The perspectives for granting a marketing authorisation to a FCH preparation are briefly analysed.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700012
Editor:  Instituto de Tecnologia do Paraná - Tecpar
Relação:  10.1590/S1516-89132008000700012
Formato:  text/html
Fonte:  Brazilian Archives of Biology and Technology v.51 n.spe 2008
Direitos:  info:eu-repo/semantics/openAccess
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