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Provedor de dados:  BABT
País:  Brazil
Título:  Glycogen levels and energy status of the liver of fasting rats with diabetes types 1 and 2
Autores:  Oliveira,Denise Silva de
Amado,Ciomar Aparecida Bersani
Martini,Mirian Carvalho
Suzuki-Kemmelmeier,Fumie
Bracht,Adelar
Data:  2007-09-01
Ano:  2007
Palavras-chave:  Diabetes type 1
Diabetes type 2
Rats
Hepatic glycogen
Hepatic energy status
Resumo:  Glycogen levels and the energy status of livers from fasting rats with diabetes types 1 and 2 were measured. After a 24 h fast, the hepatic glycogen levels of rats with diabetes1 and diabetes2 were, 18.7 and 2.6 times higher, respectively, than those of livers from the normal rats. In diabetes1 rats, the glycogen levels decreased when the fasting period was extended to 48 and 72 h. The opposite occurred with the control and diabetes2 rats. Consistently, glucose release by the perfused livers from diabetes1 rats was considerably higher during at least 60 minutes after initiating perfusion. The hepatic ATP content of diabetes1 rats was similar to that of the control rats; in diabetes2 rats, the hepatic ATP content was increased. It could be concluded that regulation of glycogen deposition and degradation in rats with diabetes1 differed markedly from that of rats with diabetes2 which, in turn, behaved similarly to normal healthy rats.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000500006
Editor:  Instituto de Tecnologia do Paraná - Tecpar
Relação:  10.1590/S1516-89132007000500006
Formato:  text/html
Fonte:  Brazilian Archives of Biology and Technology v.50 n.5 2007
Direitos:  info:eu-repo/semantics/openAccess
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