| Registro completo |
| Provedor de dados: |
BABT
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| País: |
Brazil
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| Título: |
Detection of Lsr2 gene of Mycobacterium leprae in nasal mucus
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| Autores: |
Custodio,Luiz Antonio
Saito,Alexandre
Amarante,Marla Karine
Fujita,Thiago Cezar
Perim,Aparecida de Lourdes
Costa,Ivete Conchon
Felipe,Ionice
Jankevicius,Shiduca Itow
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| Data: |
2012-06-01
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| Ano: |
2012
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| Palavras-chave: |
Mycobacterium leprae
Leprosy
Hanseniase
Nasal mucus
PCR
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| Resumo: |
In the present study, nasal mucus from patients with leprosy were analyzed by PCR using specific primers for Lsr2 gene of Mycobacterium leprae. The presence of Lsr2 gene in the nasal mucus was detected in 25.80% of patients with paucibacillari leprosy, and 23.07% of contacts. Despite the absence of clinical features in the contact individuals, it was possible to detect the presence of Lsr2 gene in the nasal mucus of these individuals. Therefore, PCR detection of M. leprae targeting Lsr2 gene using nasal mucus samples could contribute to early diagnosis of leprosy.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000300007
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| Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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| Relação: |
10.1590/S1516-89132012000300007
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| Formato: |
text/html
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| Fonte: |
Brazilian Archives of Biology and Technology v.55 n.3 2012
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| Direitos: |
info:eu-repo/semantics/openAccess
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