| Registro completo |
| Provedor de dados: |
BABT
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| País: |
Brazil
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| Título: |
High-yield production of scutellaria radix flavonoids (baicalein, baicalin and wogonin) by liquid-culture of Scutellaria baicalensis root-derived cells
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| Autores: |
Ohtsuki,Takashi
Himeji,Mika
Fukazawa,Harumi
Tanaka,Miho
Yamamoto,Hisako
Mimura,Akio
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| Data: |
2009-04-01
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| Ano: |
2009
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| Palavras-chave: |
Antioxidant
Flavonoids
Liquid culture
High-yield production
Scutellaria baicalensis
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| Resumo: |
Production of baicalein, baicalin and wogonin by liquid culture of Scutellaria baicalensis cells derived from the plant root was studied. The maximum production obtained were 119 mg/L of baicalein at two week, 1372 mg/L of baicalin at eight week, and 14 mg/L of wogonin at two week. In addition, the production of baicalin was drastically increased to 1000 mg/L level at 3-week culture, and the extremely high production rate (339 mg/L•week) was obtained. In the comparison of total antioxidative activities among baicalein, baicalin and wogonin, evaluated by thiocyanate method, it was suggested that the location of hydroxyl groups both at 5- and 6-position contributed to enhancement of radical scavenging activity, and/or methoxylation at 8-position diminished the activity. The possibility of utilizing these flavonoids for natural antioxidants and medicine is also discussed.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200005
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| Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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| Relação: |
10.1590/S1516-89132009000200005
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| Formato: |
text/html
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| Fonte: |
Brazilian Archives of Biology and Technology v.52 n.2 2009
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| Direitos: |
info:eu-repo/semantics/openAccess
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