| Registro completo |
| Provedor de dados: |
BABT
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| País: |
Brazil
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| Título: |
Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo
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| Autores: |
Sá,Rita de Cássia da Silveira e
Leite,Magda Narciso
Peters,Vera Maria
Guerra,Martha de Oliveira
Almeida,Reinaldo Nóbrega de
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| Data: |
2006-07-01
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| Ano: |
2006
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| Palavras-chave: |
Mikania glomerata
Mutagenicity
Wistar rat
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| Resumo: |
This work makes an assessment of the dominant lethality of Mikania glomerata in male Wistar rats. Adult male received 1 mL of M. glomerata hydroalcoholic extract at a dose level of 3.3 g/kg body weight for 52 days and were mated with untreated females for seven weeks (group 1) or one week prior to the beginning of treatment and on the week following the end of treatment (group 2). The parameters analyzed were: number of implanted embryos, resorptions and corpora lutea; mating, gestation, preimplantation loss, implantation and resorption indexes (group 1); number of offspring and weaning animals (group 2). The administration of M. glomerata did not show any impairment of fertility and no significant difference in the parameters analyzed, suggesting an absence of mutagenic effect on Wistar rats.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500009
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| Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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| Relação: |
10.1590/S1516-89132006000500009
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| Formato: |
text/html
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| Fonte: |
Brazilian Archives of Biology and Technology v.49 n.4 2006
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| Direitos: |
info:eu-repo/semantics/openAccess
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