Registro completo |
Provedor de dados: |
BABT
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País: |
Brazil
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Título: |
The effect of melatonin and/or complex vitamin B1,B6,B12 in modulating epinephrine-induced stress in male rats
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Autores: |
EL-Toweissy,Mona Yossef
Mohamed,Nema Abdel-Hameed
Abdel-Wahab,Wessam Mohamed
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Data: |
2013-06-01
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Ano: |
2013
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Palavras-chave: |
Stress
Epinephrine
Melatonin
Tri-B
Rats
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Resumo: |
This study was undertaken to determine the modulating effects of intramuscular administration of melatonin (MT)(1mg/ kg) and/or Tri-B (B 1 , B 6 and B 12 ) (20mg/kg) on body weight and some biochemical changes in rats induced by Epinephrine (Epi) injection. The data showed that MT and/or Tri-B treatment effectively improved the changes in malondialdehyde, lipid profile, blood sugar level and insulin. MT and/or Tri-B administration following Epi improved partially the decrease in body weight and liver glycogen levels. Tri B injection following Epi partialy improved all the tested parameters except malondialdehyde and blood sugar level that completely improved in stressed rats. It was evident that a combination of MT and vitamin B complex had protective actions and further it was better than either of them introduced alone in stressed rats. The possible interaction between MT and Tri B provided further support to MT synergistic actions with the aim of advocating MT and Tri B as a possible synergistic therapy.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000300007
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Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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Relação: |
10.1590/S1516-89132013000300007
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Formato: |
text/html
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Fonte: |
Brazilian Archives of Biology and Technology v.56 n.3 2013
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Direitos: |
info:eu-repo/semantics/openAccess
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