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Provedor de dados:  BABT
País:  Brazil
Título:  The effect of melatonin and/or complex vitamin B1,B6,B12 in modulating epinephrine-induced stress in male rats
Autores:  EL-Toweissy,Mona Yossef
Mohamed,Nema Abdel-Hameed
Abdel-Wahab,Wessam Mohamed
Data:  2013-06-01
Ano:  2013
Palavras-chave:  Stress
Epinephrine
Melatonin
Tri-B
Rats
Resumo:  This study was undertaken to determine the modulating effects of intramuscular administration of melatonin (MT)(1mg/ kg) and/or Tri-B (B 1 , B 6 and B 12 ) (20mg/kg) on body weight and some biochemical changes in rats induced by Epinephrine (Epi) injection. The data showed that MT and/or Tri-B treatment effectively improved the changes in malondialdehyde, lipid profile, blood sugar level and insulin. MT and/or Tri-B administration following Epi improved partially the decrease in body weight and liver glycogen levels. Tri B injection following Epi partialy improved all the tested parameters except malondialdehyde and blood sugar level that completely improved in stressed rats. It was evident that a combination of MT and vitamin B complex had protective actions and further it was better than either of them introduced alone in stressed rats. The possible interaction between MT and Tri B provided further support to MT synergistic actions with the aim of advocating MT and Tri B as a possible synergistic therapy.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000300007
Editor:  Instituto de Tecnologia do Paraná - Tecpar
Relação:  10.1590/S1516-89132013000300007
Formato:  text/html
Fonte:  Brazilian Archives of Biology and Technology v.56 n.3 2013
Direitos:  info:eu-repo/semantics/openAccess
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