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Provedor de dados:  BJID
País:  Brazil
Título:  How are HCV-infected patients being identified in Brazil: a multicenter study
Autores:  Portari-Filho,Luiz H.
Álvares-da-Silva,Mario R.
Gonzalez,Aline
Ferreira,Adalgisa P.
Nogueira,Cristiane V.
Mendes-Correa,Maria C.
Lima,José M.
Lopes,Edmundo P.
Brandão,Carlos E.
Ivantes,Cláudia
Lyra,André
Lindenberg,Andreia
Ferraz,Maria L.
Data:  2019-01-01
Ano:  2019
Palavras-chave:  Epidemiology
Hepatitis C
HCV
Brazil
Resumo:  ABSTRACT Background: Hepatitis C is an important health problem. In Brazil, 1-2 million people are infected. Despite this expressive number, and the availability of very successful treatment, many patients remained undiagnosed mainly because of the asymptomatic nature of the infection. Objectives: To describe epidemiological characteristics of HCV-infected patients seen at referral centers in Brazil, the source of referral, and the time spanned to reach a reference center, in order to improve the identification of undiagnosed patients. Methods: Multicenter observational, cross-sectional study carried out in 15 centers of Brazil, between January/2016 and June/2017. Data of patients with a confirmed diagnosis (anti-HCV and HCV-RNA) were collected by interview using standard questionnaires and by review of charts. Results: Two thousand patients were included; 55.1% were male, mean age 58 ± 11 years. Only 14.9% had higher education and 84.2% received up to five monthly minimum Brazilian wages (approximately US$260.00/month). The time between diagnosis and beginning of follow-up was 22.9 months. The most common reasons for testing were check-up (33.2%) and blood donation (19%). General practitioners diagnosed most of the patients (30.1%). Fibrosis stage was mainly evaluated by liver biopsy (61.5%) and 31.3% of the patients were cirrhotic at diagnosis. Conclusions: This multicenter Brazilian study showed that the mean time to reach a referral center for treatment was almost two years. Primary care physicians diagnoses most hepatitis C cases in the country. Population campaigns and medical education should be encouraged to intensify screening of asymptomatic individuals, considering the efficiency of check-ups in identifying new patients.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000100034
Editor:  Brazilian Society of Infectious Diseases
Relação:  10.1016/j.bjid.2019.01.006
Formato:  text/html
Fonte:  Brazilian Journal of Infectious Diseases v.23 n.1 2019
Direitos:  info:eu-repo/semantics/openAccess
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