| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
High prevalence of human bocavirus 1 in infants with lower acute respiratory tract disease in Argentina, 2007 - 2009
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| Autores: |
Ghietto,Lucía María
Cámara,Alicia
Zhou,Yumei
Pedranti,Mauro
Ferreyra,Silvia
Frey,Teryl
Cámara,Jorge
Adamo,Maria Pilar
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| Data: |
2012-02-01
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| Ano: |
2012
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| Palavras-chave: |
Human bocavirus 1
Infant
Bronchiolitis
Pneumonia
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| Resumo: |
Human bocavirus (HBoV) is a parvovirus whose association with respiratory disease is currently under investigation. OBJECTIVE: To determine HBoV prevalence in children with lower acute respiratory infection. METHODS: We investigated HBoV in 433 nasopharyngeal aspirates collected in 2007-2009 from children 0 to 5 years old hospitalized with bronchiolitis or pneumonia in Córdoba, Argentina. RESULTS: The general prevalence of HBoV was 21.5% and the positive cases (HBoV+) were more frequent during winter and spring. The mean age of HBoV+ patients was 6.9 months, with 87.1% of the detections corresponding to infants less than 1 year old (among which the prevalence of HBoV was 26.3% in patients < 3 months of age, 22.1% in 3 to 6 months, 25.3% in 6 to 9 months, and 18.8% in 9 to 12 months). The sequence analysis of the NP1 coding region of 15 isolates showed that all isolates from Cordoba were HBoV1 which exhibited a homology of nearly 100% both among themselves and with the originally discovered virus from 2005. CONCLUSION: Overall, our results indicate that HBoV is a significant pathogen that contributes to acute respiratory infection both on its own and during coinfection with other viruses.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000100007
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1590/S1413-86702012000100007
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.16 n.1 2012
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| Direitos: |
info:eu-repo/semantics/openAccess
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