| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
Clinical presentation and follow up of children with congenital toxoplasmosis in Brazil
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| Autores: |
Sáfadi,Marco A. P.
Berezin,Eitan N.
Farhat,Calil K.
Carvalho,Eduardo S.
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| Data: |
2003-10-01
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| Ano: |
2003
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| Palavras-chave: |
Congenital toxoplasmosis
Chorioretinitis
Neurologic manifestation
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| Resumo: |
We evaluated the clinical presentation and determined the ocular and neurologic sequelae in children with congenital toxoplasmosis in Brazil, taking into consideration the shortage of national publications on this disease. Follow-up evaluations were made of 43 children with congenital toxoplasmosis referred to Santa Casa de São Paulo, during a period of at least five years. Selection of the cases was based in clinical and laboratory criteria. A clear predominance of children with subclinical presentation of the disease at birth (88%) was found. Of the 43 children, 22 (51%) developed neurological manifestations. Using skull radiography, we detected neuroradiologic alterations in seven children (16%) and with tomography in 33 children (77%). Neurological sequelae were identified in 15 children (54%) in the group with cerebral calcifications and in 7 (47%) in the group without cerebral calcifications. We observed chorioretinitis in 95% of the cases. Reactivation of cicatricial lesions and the emergence of new ocular lesions were observed in five cases. The most frequent neurological manifestation was a delay in neuropsychomotor development. Most remarkable was the finding that cerebral calcifications were not associated with a higher incidence of neurological sequelae among the children. Chorioretinitis was the main ocular sequel of the infection, found in nearly all children; it can manifest years from birth, even in children submitted to specific therapy during the first year of life, highlighting the importance of a follow-up of these children.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000500007
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1590/S1413-86702003000500007
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.7 n.5 2003
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| Direitos: |
info:eu-repo/semantics/openAccess
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