| Registro completo |
| Provedor de dados: |
56
|
| País: |
Brazil
|
| Título: |
Vancomycin-resistant enterococcus outbreak in a pediatric intensive care unit: report of successful interventions for control and prevention
|
| Autores: |
Carmona,F.
Prado,S.I.
Silva,M.F.I.
Gaspar,G.G.
Bellissimo-Rodrigues,F.
Martinez,R.
Matsuno,A.K.
Carlotti,A.P.C.P.
|
| Data: |
2012-02-01
|
| Ano: |
2012
|
| Palavras-chave: |
Infections
Antibiotics misuse
Drug resistance
Vancomycin-resistant enterococcus
|
| Resumo: |
The objective of this study is to retrospectively report the results of interventions for controlling a vancomycin-resistant enterococcus (VRE) outbreak in a tertiary-care pediatric intensive care unit (PICU) of a University Hospital. After identification of the outbreak, interventions were made at the following levels: patient care, microbiological surveillance, and medical and nursing staff training. Data were collected from computer-based databases and from the electronic prescription system. Vancomycin use progressively increased after March 2008, peaking in August 2009. Five cases of VRE infection were identified, with 3 deaths. After the interventions, we noted a significant reduction in vancomycin prescription and use (75% reduction), and the last case of VRE infection was identified 4 months later. The survivors remained colonized until hospital discharge. After interventions there was a transient increase in PICU length-of-stay and mortality. Since then, the use of vancomycin has remained relatively constant and strict, no other cases of VRE infection or colonization have been identified and length-of-stay and mortality returned to baseline. In conclusion, we showed that a bundle intervention aiming at a strict control of vancomycin use and full compliance with the Hospital Infection Control Practices Advisory Committee guidelines, along with contact precautions and hand-hygiene promotion, can be effective in reducing vancomycin use and the emergence and spread of vancomycin-resistant bacteria in a tertiary-care PICU.
|
| Tipo: |
Info:eu-repo/semantics/article
|
| Idioma: |
Inglês
|
| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000200011
|
| Editor: |
Associação Brasileira de Divulgação Científica
|
| Relação: |
10.1590/S0100-879X2012007500005
|
| Formato: |
text/html
|
| Fonte: |
Brazilian Journal of Medical and Biological Research v.45 n.2 2012
|
| Direitos: |
info:eu-repo/semantics/openAccess
|
|
