Registro completo |
Provedor de dados: |
BJM
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País: |
Brazil
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Título: |
Prevalence of the precore G1896A mutation in Chinese patients with e antigen negative hepatitis B virus infection and its relationship to pre-S1 antigen
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Autores: |
Zhang,Jing
Xu,Wei-Jia
Wang,Qing
Zhang,Yong
Shi,Ming
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Data: |
2009-12-01
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Ano: |
2009
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Palavras-chave: |
Hepatitis B virus
Precore mutation
Pre-S1
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Resumo: |
This study investigated the prevalence of the precore G1896A mutation in Chinese patients with hepatitis B e antigen (HBeAg) negative HBV infection and its relation to serum HBV pre-S1 antigen. The overall prevalence of the precore G1896A mutation was 72.6% in HBeAg-negative Chinese patients with detectable serum HBV DNA. The prevalence of the precore G1896A is significantly higher in Chinese HBeAg-negative patients with chronic hepatitis B than that in inactive HBV carriers with detectable serum HBV DNA. Serum pre-S1 and the precore G1896A mutation were simultaneously detected in most of Chinese HBeAg-negative patients.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000400031
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Editor: |
Sociedade Brasileira de Microbiologia
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Relação: |
10.1590/S1517-83822009000400031
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Formato: |
text/html
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Fonte: |
Brazilian Journal of Microbiology v.40 n.4 2009
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Direitos: |
info:eu-repo/semantics/openAccess
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