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Provedor de dados:  BJM
País:  Brazil
Título:  Cytotoxicity of subfractions and compounds from Polymnia sonchifolia
Autores:  Fernandes,Maria Judite B.
Limas,Caroline
Rossi,Maria Helena
Gonçales,Edlayne
Simoni,Isabela C.
Data:  2005-12-01
Ano:  2005
Palavras-chave:  Polymnia sonchifolia
Subfractions
Lactones
Cytotoxicity
Crystal violet staining (CVS) method
Resumo:  Our previous works showed that extracts and fractions from Polymnia sonchifolia had presented an inhibitory activity on growth and aflatoxin production by Aspergillus flavus in non-cytotoxic concentrations. In this work, report results on the in vitro cytotoxicity of subfractions and of a mixture of sesquiterpenes lactones from Polymnia sonchifolia on Vero cells. The cytotoxicity was assayed through crystal violet staining (CVS) method and the 50% inhibitory concentration for cell growth (IC50) was calculated. Both subfractions and the mixture of sesquiterpenes lactones did not show in vitro cytotoxicity to Vero cells on active biologically concentrations against production of aflatoxin B1 by Aspergillus flavus.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822005000400006
Editor:  Sociedade Brasileira de Microbiologia
Relação:  10.1590/S1517-83822005000400006
Formato:  text/html
Fonte:  Brazilian Journal of Microbiology v.36 n.4 2005
Direitos:  info:eu-repo/semantics/openAccess
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