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Provedor de dados:  BJM
País:  Brazil
Título:  Torque teno virus among dialysis and renal-transplant patients
Autores:  Takemoto,Angélica Yukari
Okubo,Patrícia
Saito,Patricia Keiko
Yamakawa,Roger Haruki
Watanabe,Maria Angélica Ehara
Veríssimo da Silva Junior,Waldir
Borelli,Sueli Donizete
Bedendo,João
Data:  2015-03-01
Ano:  2015
Palavras-chave:  Torque teno virus
Renal dialysis
Kidney transplant
Infection
Resumo:  Patients who undergo dialysis treatment or a renal transplant have a high risk of blood-borne viral infections, including the Torque teno virus (TTV). This study identified the presence of TTV and its genome groups in blood samples from 118 patients in dialysis and 50 renal-transplant recipients. The research was conducted in a hospital in the city of Maringá, state of Paraná. The viral DNA, obtained from whole blood, was identified by using two nested Polymerase Chain Reactions (PCR). The frequencies of TTV were 17% and 36% in dialysis patients using the methodology proposed by Nishizawa et al. (1997) and Devalle and Niel (2004), respectively, and 10% and 54% among renal-transplant patients. There was no statistically significant association between the frequency of the pathogen and the variables: gender, time in dialysis, time since transplant, blood transfusions, and the concomitant presence of hepatitis B, for either the dialysis patients or the renal-transplant recipients. Among dialysis patients and renal-transplant recipients, genogroup 5 was predominant (48% and 66% respectively), followed by genogroup 4 (37% and 48%) and genogroup 1 (23% and 25%). Genogroup 2 was present in both groups of patients. Some patients had several genogroups, but 46% of the dialysis patients and 51% of the renal-transplant recipients had only a single genogroup. This study showed a high prevalence of TTV in dialysis patients and renal-transplant recipients.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100307
Editor:  Sociedade Brasileira de Microbiologia
Relação:  10.1590/S1517-838246120131195
Formato:  text/html
Fonte:  Brazilian Journal of Microbiology v.46 n.1 2015
Direitos:  info:eu-repo/semantics/openAccess
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