| Registro completo |
| Provedor de dados: |
BJPS
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| País: |
Brazil
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| Título: |
Phage therapy: progress in pharmacokinetics
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| Autores: |
Qadir,Muhammad Imran
Mobeen,Tahira
Masood,Ardas
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| Data: |
2018-01-01
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| Ano: |
2018
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| Palavras-chave: |
Phage therapy/pharmacology
Pharmacokinetics
Delivery systems
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| Resumo: |
ABSTRACT The concept of phage therapy exists in the history and it has been ignored for a long time, but the consequence of drug resistance in pathogen bacteria has forced the forgotten kingdom of phage therapy to be re-explored. However, for the successful implementation and acceptance of phage therapy worldwide, the number of factors need to be addressed. In pharmacology of phage therapy, pharmacodynamics is a straightforward concept, on the other hand, owing to the unique feature of phages to replicate and their high sensitivity, pharmacokinetics is rather complex. In this review, we have discussed pharmacokinetics and some recent advances in delivery systems as to achieve the therapeutically effective concentrations of phage in their activated form.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100402
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| Editor: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
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| Relação: |
10.1590/s2175-97902018000117093
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Pharmaceutical Sciences v.54 n.1 2018
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| Direitos: |
info:eu-repo/semantics/openAccess
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