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Provedor de dados:  BJPS
País:  Brazil
Título:  Pancreatic beta cell protection/regeneration with phytotherapy
Autores:  Hosseini,Azar
Shafiee-Nick,Reza
Ghorbani,Ahmad
Data:  2015-03-01
Ano:  2015
Palavras-chave:  Diabetes mellitus/treatment
Diabetes mellitus/phytotherapy
Phytotherapy/Diabetes mellitus
Islets/endogenous regeneration
Beta cells/protection
Beta cells/regeneration
Pancreas
Medicinal plants/regenerative properties
Resumo:  Although currently available drugs are useful in controlling early onset complications of diabetes, serious late onset complications appear in a large number of patients. Considering the physiopathology of diabetes, preventing beta cell degeneration and stimulating the endogenous regeneration of islets will be essential approaches for the treatment of insulin-dependent diabetes mellitus. The current review focused on phytochemicals, the antidiabetic effect of which has been proved by pancreatic beta cell protection/regeneration. Among the hundreds of plants that have been investigated for diabetes, a small fraction has shown the regenerative property and was described in this paper. Processes of pancreatic beta cell degeneration and regeneration were described. Also, the proposed mechanisms for the protective/regenerative effects of such phytochemicals and their potential side effects were discussed.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100001
Editor:  Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação:  10.1590/S1984-82502015000100001
Formato:  text/html
Fonte:  Brazilian Journal of Pharmaceutical Sciences v.51 n.1 2015
Direitos:  info:eu-repo/semantics/openAccess
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