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Provedor de dados:  BJPS
País:  Brazil
Título:  Intravenous immunoglobulin therapy among pediatric patients: labeled and off-labeled indications
Autores:  Toh,Chin Chiang
Islahudin,Farida
Ali,Adli
Shah,Noraida Mohamed
Data:  2018-01-01
Ano:  2018
Palavras-chave:  Intravenous Immunoglobulin
Off-label indications
Pediatric patients
Malaysia hospital
Resumo:  ABSTRACT This study was designed to evaluate utilization patterns and clinical outcome of intravenous immunoglobulin (IVIG) therapy among pediatric patients in a tertiary hospital. Demographic data, IVIG prescribed, and clinical outcome were retrospectively reviewed from the pharmacy dispensing data and patient medical records between 2007 and 2014. One hundred and fifteen instances of IVIG administration to 108 pediatric patients were recorded. A total of 61 cases (53%) and 54 cases (47%) of the IVIG administered were for labeled and off-labeled indications, respectively. Age, weight, specialty, total IVIG usage, length of hospital stays, and mortality rate were found to be significantly associated with the indication being labeled or off-labeled (p<0.05). However, there was no significant difference in terms of adverse reactions between labeled and off-labeled indications (p>0.05). Guidelines should be developed and implemented for rational and evidence-based use of IVIG to avoid unnecessary wastage.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100601
Editor:  Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação:  10.1590/s2175-97902018000100008
Formato:  text/html
Fonte:  Brazilian Journal of Pharmaceutical Sciences v.54 n.1 2018
Direitos:  info:eu-repo/semantics/openAccess
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