| Registro completo |
| Provedor de dados: |
BJPS
|
| País: |
Brazil
|
| Título: |
Central activities of hydroalcoholic extract from Lafoensia pacari A. St.-Hil. stem bark
|
| Autores: |
Galdino,Pablinny Moreira
Nascimento,Marcus Vinícius Mariano
Sousa,Fábio Borges de
Ferreira,Reginaldo Nassar
Paula,José Realino de
Costa,Elson Alves
|
| Data: |
2010-09-01
|
| Ano: |
2010
|
| Palavras-chave: |
Lafoensia pacari A. St.-Hil/pharmacognosy
Hydroalcoholic extract
Central Nervous System/experimental study
Anxiety/experimental study
|
| Resumo: |
Lafoensia pacari A. St.-Hil. can be found from Amapá to Rio Grande do Sul states, and also in Paraguay and Bolivia. It is popularly known as pacari or mangava-brava and is used to promote weight loss, as an anti-thermal or tonic, to treat gastritis, ulcers, scarring, itching, discouragement, and cancer. In the open field tests, the hydroalcoholic extract from L. pacari stem bark (HEP) decreased the number of rearings, number of invaded squares, and increased immobility time compared to control animals. In the pentobarbital-induced sleep time test, HEP decreased latency time to sleep and increased sleeping time. In the rota-rod test, no changes in the studied parameters were observed. In the elevated plus maze, HEP increased the percentage time and percentage entries in the open arms, indicating that this extract exerts an anxiolytic-like activity.
|
| Tipo: |
Info:eu-repo/semantics/article
|
| Idioma: |
Inglês
|
| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300008
|
| Editor: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
|
| Relação: |
10.1590/S1984-82502010000300008
|
| Formato: |
text/html
|
| Fonte: |
Brazilian Journal of Pharmaceutical Sciences v.46 n.3 2010
|
| Direitos: |
info:eu-repo/semantics/openAccess
|
|
