| Registro completo |
| Provedor de dados: |
BJPS
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| País: |
Brazil
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| Título: |
Isolation of flavonoids from Anemopaegma arvense (Vell) Stellf. ex de Souza and their antifungal activity against Trichophyton rubrum
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| Autores: |
Costanzo,Camila Di Giovane
Fernandes,Vanessa Colnaghi
Zingaretti,Sônia
Beleboni,Rene Oliveira
Pereira,Ana Maria Soares
Marins,Mozart
Taleb-Contini,Sílvia Helena
Pereira,Paulo Sérgio
Fachin,Ana Lúcia
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| Data: |
2013-09-01
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| Ano: |
2013
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| Palavras-chave: |
Bignoniaceae
Anemopaegma arvense/phytochemistry
Catuaba/phytochemistry
Flavonoids/antifungal activity
Plant extract/evaluation
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| Resumo: |
Anemopaegma arvense (Vell) Stellf. ex de Souza belongs to the family Bignoniaceae, and is popularly known as catuaba. To evaluate the cytotoxic and antimicrobial activity of A. arvense, fraction F3 and flavonoids 1 (quercetin 3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside) (rutin) and flavonoid 2 (quercetin 3-O-α-L-rhamnopyranosyl-(1→6)-β-D-galactopyranoside) were isolated from the leaves of this plant. Fraction F3 and flavonoids 1 and 2 exhibited no antibacterial activity. Furthermore, no cytotoxic activity of fraction 3 or flavonoids 1 and 2 was observed against the tumor cells tested. However, analysis of the antifungal activity of flavonoids 1 and 2 revealed minimum inhibitory concentrations of 0.5 and 0.25 mg/mL, respectively, against the Trichophyton rubrum strains tested (wild type and mutant). This study demonstrates for the first time the antifungal activity of isolated flavonoids, validating the same activity for A. arvense.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300017
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| Editor: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
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| Relação: |
10.1590/S1984-82502013000300017
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Pharmaceutical Sciences v.49 n.3 2013
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| Direitos: |
info:eu-repo/semantics/openAccess
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