| Registro completo |
| Provedor de dados: |
Ciência Rural
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| País: |
Brazil
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| Título: |
Mammary fibroadenomatoid hyperplasia in a heifer
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| Autores: |
Silva,Lorena Ferreira
Silva,Luiz Antonio Franco da
Rabelo,Rogério Elias
Silva,Wanessa Patrícia Rodrigues da
Cassali,Geovanni Dantas
Gonçalves,Aline De Biasi Bassani
Sant’Ana,Fabiano José Ferreira de
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| Data: |
2017-01-01
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| Ano: |
2017
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| Palavras-chave: |
Mammary hyperplasia
Estrogen
Progesterone
Diseases of cattle
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| Resumo: |
ABSTRACT: This manuscript described the anatomopathological and immunohistochemical findings in a rare case of mammary fibroadenomatoid hyperplasia in a 12-month-old Holstein heifer. A yellow, multilobulated, firm 20cm x 9cm x 6.5cm mass affecting the right quarters of the udder was observed. Total mastectomy was performed. Microscopic evaluation revealed severe hyperplasia of the mammary epithelium and numerous well-differentiated and mildly pleomorphic acini. Additionally, moderate proliferation of the fibrous connective tissue and the myoepithelial cells near the proliferating acini was evident. About 50% of the proliferating epithelial cells showed positive nuclear labeling for estrogen and progesterone receptors, and approximately one-third were positive for Ki-67. In addition, the myoepithelial cells exhibited diffuse nuclear immunoreactivity for p63. Based on the clinical, morphologic, and immunohistochemical findings, a diagnosis of mammary fibroadenomatoid hyperplasia with probable influence of ovarian steroids was made.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000600552
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| Editor: |
Universidade Federal de Santa Maria
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| Relação: |
10.1590/0103-8478cr20160943
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| Formato: |
text/html
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| Fonte: |
Ciência Rural v.47 n.6 2017
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| Direitos: |
info:eu-repo/semantics/openAccess
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