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Provedor de dados:  Ciência Rural
País:  Brazil
Título:  Lissencephaly and cerebellar hypoplasia in a goat
Autores:  Santos,José Rômulo Soares dos
Dantas,Antônio Flavio Medeiros
Pessoa,Clarice Ricardo Macedo
Silva,Tatiane Rodrigues
Simões,Sara Vilar Dantas
Correa,Franklin Riet
Pedrosa,Daniel
Data:  2013-10-01
Ano:  2013
Palavras-chave:  Agyria
Cerebellar hypoplasia goat malformations
Resumo:  A case of lissencephaly and cerebellar hypoplasia was observed in a 30-day-old goat. The goat presented with sternal recumbence, absence of a menace response, intention tremors, ataxia, and nystagmus. The goat was euthanized and necropsied after having been hospitalised for eleven days. At necropsy, the surface of the brain was found to be smooth, the cerebral sulci and gyri were absent, and the cerebellum was reduced in size. Histologically, the grey matter and white matter were thicker and thinner than normal in cortices, respectively. The neurons were randomly arranged in the grey matter. In the cerebellum, the layers were disorganised, and cells were heterotopics. The histologic and gross lesions observed in this animal are characteristic of lissencephaly associated with cerebellar hypoplasia. The presence of a single goat affected suggests that the malformation was not of infectious origin and because lissencephaly is a malformation not previously described in goats, it is unlikely this case was inherited.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013001000020
Editor:  Universidade Federal de Santa Maria
Relação:  10.1590/S0103-84782013001000020
Formato:  text/html
Fonte:  Ciência Rural v.43 n.10 2013
Direitos:  info:eu-repo/semantics/openAccess
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