| Registro completo |
| Provedor de dados: |
Ciência Rural
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| País: |
Brazil
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| Título: |
Peripheral neuropathy in a copper-deficient goat
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| Autores: |
Almeida,Valdir Morais de
Chaves,Hisadora Advincula da Silva
Silva Filho,Givaldo Bom da
Ribeiro,Danielle Pimentel
Braga,Thaiza Campelo
Mendonça,Fábio de Souza
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| Data: |
2017-01-01
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| Ano: |
2017
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| Palavras-chave: |
Mineral deficiency
Paralysis
Monoplegia
Muscular atrophy
Ruminants
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| Resumo: |
ABSTRACT: This report aimed to describe a case of peripheral neuropathy in a copper-deficient goat, and highlights the clinical, and pathological features of the disease. The goat had low body score, hyporexia, alopecia, achromotrichia, left hindlimb protraction, paralysis with dragging of digit and difficulty to stand up and microcytic normochromic anemia. Copper concentration in serum was markedly lower (2.0µmol L-1) whereas the iron serum content was significantly increased (51.0µmol L-1). The main gross alteration was the reduction of the quadriceps vastus laterallis muscle volume. Histologically, there was atrophy of the quadriceps vastus laterallis muscle and presence of satellite cells, infiltration of lymphocytes, macrophages and replacement of the fibers by connective tissue. In the femoral nerve, there was axonal degeneration with myelin sheath expansion and presence of vacuoles, usually in chains and containing axonal debris or macrophages. Clinical, laboratorial and pathologic findings are consistent with peripheral neuropathy due to a severy copper deficiency.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001000552
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| Editor: |
Universidade Federal de Santa Maria
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| Relação: |
10.1590/0103-8478cr20170248
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| Formato: |
text/html
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| Fonte: |
Ciência Rural v.47 n.10 2017
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| Direitos: |
info:eu-repo/semantics/openAccess
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