| Registro completo |
| Provedor de dados: |
Ciência Rural
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| País: |
Brazil
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| Título: |
Cyclooxygenase-2 expression in epithelial neoplasms and its relevance as a targeted therapy in dogs
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| Autores: |
Cunha,Rúbia Monteiro de Castro
Horta,Rodrigo dos Santos
Lavalle,Gleidice Eunice
Araújo,Roberto Baracat
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| Data: |
2016-06-01
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| Ano: |
2016
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| Palavras-chave: |
Cancer
Carcinoma
Immunohistochemistry
Antineoplastic drugs.
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| Resumo: |
ABSTRACT: Targeted therapy of neoplasms is an emergent approach in human and veterinary medicine. Cyclooxygenase (COX) is a class of catalytic enzymes related to the formation of inflammatory mediators. COX-2 is expressed constitutively in a few body tissues, but it may be induced in specific pathophysiologic conditions, such as cancer. COX-2 expression in neoplams may be considered a potential predictive factor, due to the possible association of selective COX-2 inhibitors in adjuvant treatments. This scientific communication has the objective to report COX-2 expression in seven neoplasms of dogs and the usage of adjuvant treatment with COX-2 selective inhibitors as an effective and feasible option in cancer treatment.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000601050
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| Editor: |
Universidade Federal de Santa Maria
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| Relação: |
10.1590/0103-8478cr20150794
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| Formato: |
text/html
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| Fonte: |
Ciência Rural v.46 n.6 2016
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| Direitos: |
info:eu-repo/semantics/openAccess
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