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Provedor de dados:  Electron. J. Biotechnol.
País:  Chile
Título:  Data mining and influential analysis of gene expression data for plant resistance gene identification in tomato (Solanum lycopersicum)
Autores:  Torres-Avilés,Francisco
Romeo,José S
López-Kleine,Liliana
Data:  2014-03-01
Ano:  2014
Palavras-chave:  Classification
Data mining
Functional gene prediction
GEE models
Gene expression data
Plant immunity genes
Resumo:  Background Molecular mechanisms of plant-pathogen interactions have been studied thoroughly but much about them is still unknown. A better understanding of these mechanisms and the detection of new resistance genes can improve crop production and food supply. Extracting this knowledge from available genomic data is a challenging task. Results Here, we evaluate the usefulness of clustering, data-mining and regression to identify potential new resistance genes. Three types of analyses were conducted separately over two conditions, tomatoes inoculated with Phytophthora infestans and not inoculated tomatoes. Predictions for 10 new resistance genes obtained by all applied methods were selected as being the most reliable and are therefore reported as potential resistance genes. Conclusion Application of different statistical analyses to detect potential resistance genes reliably has shown to conduct interesting results that improve knowledge on molecular mechanisms of plant resistance to pathogens.
Tipo:  Journal article
Idioma:  Inglês
Identificador:  http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000200004
Editor:  Pontificia Universidad Católica de Valparaíso
Formato:  text/html
Fonte:  Electronic Journal of Biotechnology v.17 n.2 2014
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