| Registro completo |
| Provedor de dados: |
Genet. Mol. Biol.
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| País: |
Brazil
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| Título: |
Association of PPARγ2 polymorphisms with carcass and meat quality traits in a Pietrain x Jinhua F2 population
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| Autores: |
Chen,Zhe
Zhao,Xiaofeng
Jiang,Xiaoling
Guo,Xiaoling
Lv,Zunzhou
Zhou,Hongmei
Xu,Ningying
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| Data: |
2011-01-01
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| Ano: |
2011
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| Palavras-chave: |
PPARγ2 gene
Haplotype
Carcass and meat quality
Pigs
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| Resumo: |
The PPARγ2 gene is a key regulator of both proliferation and preadipocyte differentiation in mammals. Herein its genotype and allele frequencies were analyzed using PCR-SSCP in eight pig breeds (N = 416). Two kinds of polymorphisms of the PPARγ2 gene were detected, including a previously reported shift SNP A177G (Met59Val) in exon 1 and a novel silent mutation G876A in exon 5. The results revealed that European pig breeds carry a higher allele A frequency at the A177G locus and a fixed GG genotype at the G876A locus. Allele A at the G876A locus was only found in Jinhua pigs. The association between haplotype (A177G/G876A) and carcass and meat quality traits was analyzed in a Pietrain x Jinhua F2 population (N = 248). The PPARγ2 gene was found to be significantly associated with backfat thickness at the shoulder (p < 0.05), 6-7th ribs (p < 0.01), last rib (p < 0.01), gluteus medius (p <0.05) and ham weight (p < 0.01). Significant effects of different haplotypes on ham weight and backfat thickness at the 6-7th ribs, last rib, and gluteus medius were also observed.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000100011
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| Editor: |
Sociedade Brasileira de Genética
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| Relação: |
10.1590/S1415-47572010005000107
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| Formato: |
text/html
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| Fonte: |
Genetics and Molecular Biology v.34 n.1 2011
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| Direitos: |
info:eu-repo/semantics/openAccess
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