| Registro completo |
| Provedor de dados: |
Genet. Mol. Biol.
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| País: |
Brazil
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| Título: |
A rapid detection method for PAI-1 promoter insertion/deletion polymorphism (4G/5G)
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| Autores: |
Annichino-Bizzacchi,Joyce M.
Pugliese,Luciana
Arruda,Valder R.
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| Data: |
1998-09-01
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| Ano: |
1998
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| Resumo: |
Plasminogen activator inhibitor-1 (PAI-1) is an important inhibitor of fibrinolysis, and increased levels of PAI-1 are associated with atheroma and myocardial infarction. A common 4G/5G insertion/deletion polymorphism located in the promoter region of PAI-1 gene has been described associated with PAI-1 activity in plasma levels. Genotyping of this polymorphism is commonly conducted with an allele-specific oligonucleotide melting technique. In the present study, we describe a quick, easy method for genotyping 4G/5G polymorphism in the promoter region of the PAI-1 gene.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571998000300004
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| Editor: |
Sociedade Brasileira de Genética
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| Relação: |
10.1590/S1415-47571998000300004
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| Formato: |
text/html
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| Fonte: |
Genetics and Molecular Biology v.21 n.3 1998
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| Direitos: |
info:eu-repo/semantics/openAccess
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