| Registro completo |
| Provedor de dados: |
Genet. Mol. Biol.
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| País: |
Brazil
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| Título: |
Population and mutation analysis of Y-STR loci in a sample from the city of São Paulo (Brazil)
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| Autores: |
Soares-Vieira,José A.
Billerbeck,Ana E.C.
Iwamura,Edna S.M.
Mendonca,Berenice B.
Gusmão,Leonor
Otto,Paulo A.
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| Data: |
2008-01-01
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| Ano: |
2008
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| Palavras-chave: |
Y-STR population data
São Paulo (Brazil)
Mutation rates
Duplications
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| Resumo: |
The haplotypes of seven Y-chromosome STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, and DYS393) were determined in a sample of 634 healthy Brazilian males (190 adult individuals and 222 father-son pairs). The 412 adults were unrelated, and the 222 father-son pairs had their biological relationship confirmed using autosomal STRs (LR > 10,000). Among the 412 adults, a total of 264 different 7-loci haplotypes were identified, 210 of which were unique. The most frequent haplotype was detected in 31 instances, occurring with a frequency of 7.52%. The haplotype diversity index was calculated as 98.83%. Upon transmission of the 1,554 alleles, in 222 father-son pairs, six mutations were observed, with an average overall rate of 3.86 x 10-3 per locus. A haplotype with a duplicated DYS389I locus, and another with duplicated DYS389I, DYS389II, and DYS439 loci were detected in both fathers and their respective sons.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400009
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| Editor: |
Sociedade Brasileira de Genética
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| Relação: |
10.1590/S1415-47572008000400009
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| Formato: |
text/html
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| Fonte: |
Genetics and Molecular Biology v.31 n.3 2008
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| Direitos: |
info:eu-repo/semantics/openAccess
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