| Registro completo |
| Provedor de dados: |
Genet. Mol. Biol.
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| País: |
Brazil
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| Título: |
Association of IGF-I gene polymorphisms with milk yield and body size in Chinese dairy goats
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| Autores: |
Deng,Chanjuan
Ma,Rongnuan
Yue,Xiangpeng
Lan,Xianyong
Chen,Hong
Lei,Chuzhao
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| Data: |
2010-01-01
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| Ano: |
2010
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| Palavras-chave: |
IGF-I gene
Dairy goat
Milk yield
PCR- SSCP
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| Resumo: |
The association of IGF-I gene polymorphisms with certain traits in 708 individuals of two Chinese dairy-goat breeds (Guanzhong and Xinong Saanen) was investigated. Polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and DNA sequencing methods were employed in screening for genetic variation. Two novel mutations were detected in the 5'-flanking region and in intron 4 of IGF-I gene, viz., g.1617 G > A and g.5752 G > C (accession D26119.2), respectively. The associations of the g.1617 G > A mutation with milk yield and the body size were not significant (p > 0.05). However, in the case of g.5752 G > C, Xinong Saanen dairy goats with the CG genotype presented longer bodies (p < 0.05). Chest circumference (p < 0.05) was larger in Guanzhong goats with the GG genotype. In Xinong Saanen dairy goats with the CC genotype, milk yields were significantly higher during the first and second lactations (p < 0.05). Hence, the g.5752 G > C mutation could facilitate association analysis and serve as a genetic marker for Chinese dairy-goat breeding and genetics.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000200012
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| Editor: |
Sociedade Brasileira de Genética
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| Relação: |
10.1590/S1415-47572010005000034
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| Formato: |
text/html
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| Fonte: |
Genetics and Molecular Biology v.33 n.2 2010
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| Direitos: |
info:eu-repo/semantics/openAccess
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