| Registro completo |
| Provedor de dados: |
Genet. Mol. Biol.
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| País: |
Brazil
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| Título: |
Genotoxic and mutagenic effects of polluted surface water in the midwestern region of Brazil using animal and plant bioassays
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| Autores: |
Dourado,Priscila Leocádia Rosa
Rocha,Monyque Palagano da
Roveda,Liriana Mara
Raposo Junior,Jorge Luiz
Cândido,Liliam Sílvia
Cardoso,Claudia Andréa Lima
Morales,Maria Aparecida Marin
Oliveira,Kelly Mari Pires de
Grisolia,Alexeia Barufatti
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| Data: |
2017-03-01
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| Ano: |
2017
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| Palavras-chave: |
Allium cepa
Astyanax altiparanae
Mutagenicity
Cytotoxicity
Genotoxicity
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| Resumo: |
Abstract This study aimed to evaluate DNA damage in animal and plant cells exposed to water from the Água Boa stream (Dourados, Mato Grosso do Sul, Brazil) by using bioassays, and to identify the chemical compounds in the water to determine the water quality in the area. Through the cytotoxicity bioassay with Allium cepa, using micronucleus test, and comet assay, using Astyanax altiparanae fish, the results indicated that biological samples were genetically altered. Micronuclei were observed in erythrocytes of A. altiparanae after exposure to water from locations close to industrial waste discharge. The highest DNA damage observed with the comet assay in fish occurred with the exposure to water from locations where the presence of metals (Cu, Pb, Cd, Ni) was high, indicating the possibility of genotoxic effects of these compounds. Thus, these results reinforce the importance of conducting genotoxicity tests for developing management plans to improve water quality, and indicate the need for waste management before domestic and industrial effluents are released into the rivers and streams.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000100123
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| Editor: |
Sociedade Brasileira de Genética
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| Relação: |
10.1590/1678-4685-gmb-2015-0223
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| Formato: |
text/html
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| Fonte: |
Genetics and Molecular Biology v.40 n.1 2017
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| Direitos: |
info:eu-repo/semantics/openAccess
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