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Provedor de dados:  International Journal of Morphology
País:  Chile
Título:  Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases
Autores:  Bernardes,Vanessa Fátima
Ramos-Jorge,Maria Letícia
Vieira Carmo,Maria Auxiliadora
Cardoso,Sérgio Vitorino
Alves Mesquita,Ricardo
Ferreira Aguiar,Maria Cássia
Data:  2008-12-01
Ano:  2008
Palavras-chave:  C-erbB-2
Her-2/neu
Immunohistochemistry
Mucoepidermoid carcinoma
Salivary gland neoplasms
Resumo:  The association among clinicopathological features and c-erbB-2 oncoprotein expression was evaluated in twenty-nine cases of intra-oral mucoepidermoid carcinoma (MEC). MEC was prevalent in the female gender (79.3%), tumors were more frequent in ages between 21 and 40 years (48.3%), and the palate was the most commonly affected site (72.4%). Microscopically, 27 cases (93.1%) were classified as low grade of malignancy. The c-erbB-2 expression was considered positive in 9 (31%) cases and no significant association (p>0.05) was found among protein expression and gender ñor between patient age and site or histological grade of the lesión. c-erbB-2 expression in MEC may reflect intrisinc biologic properties of salivary gland neoplasms and may be linked to histogenesis and cellular differentiaton.
Tipo:  Journal article
Idioma:  Inglês
Identificador:  http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400036
Editor:  Sociedad Chilena de Anatomía
Formato:  text/html
Fonte:  International Journal of Morphology v.26 n.4 2008
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