| Registro completo |
| Provedor de dados: |
J. Venom. Anim. Toxins incl. Trop. Dis.
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| País: |
Brazil
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| Título: |
Decrease in hepatitis B prevalence among blood donors in Central-West Brazil
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| Autores: |
Lindenberg,Andréa de Siqueira Campos
Motta-Castro,Ana Rita Coimbra
Puga,Marco Antonio
Ortiz Tanaka,Tayana Serpa
Torres,Marina Sawada
Fernandes-Fitts,Sonia Maria
Cunha,Rivaldo Venancio
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| Data: |
2013-01-01
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| Ano: |
2013
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| Palavras-chave: |
Hepatitis B virus
Prevalence
Blood donors
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| Resumo: |
Background The aim of the present study was to estimate hepatitis B virus seroprevalence among first-time blood donors in the city of Campo Grande, Mato Grosso do Sul State, in the central-western region of Brazil. Findings A retrospective analysis of first-time voluntary blood donor records, from January 2010 to December 2010, was conducted at the Hematology Center of Mato Grosso do Sul. The prevalence of the HBsAg and anti-HBc serological markers and their respective 95% confidence intervals were calculated. Chi-square analysis was performed between the seroprevalence previously found in 2001 and the one determined by the current study. Results were considered statistically significant if p < 0.05. Among 8,840 subjects, 269 (3.04%, 95% CI: 2.7-3.4) were positive for HBV markers. The prevalence rate of HBsAg was 0.19% (95% CI: 0.1-0.3) and anti-HBc alone was 2.85% (95% CI: 2.5-3.2). Conclusions There was no statistically significant difference regarding gender. However, an important association was observed between HBV infection and older age ( p < 0.01). The seroprevalence of HBV infection in first-time blood donors diminished from 2001 to 2010 ( p < 0.01). Such decrease suggests an improvement in the recruitment of safe donors, the positive impact of vaccination programs and the decreasing of HBV infection prevalence in the general population.
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| Tipo: |
Info:eu-repo/semantics/other
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992013000100402
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| Editor: |
Centro de Estudos de Venenos e Animais Peçonhentos
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| Relação: |
10.1186/1678-9199-19-7
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| Formato: |
text/html
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| Fonte: |
Journal of Venomous Animals and Toxins including Tropical Diseases v.19 2013
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| Direitos: |
info:eu-repo/semantics/openAccess
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