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| Registros recuperados: 42 | |
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| Mondelli,AL; Niéro-Melo,L; Bagagli,E; Camargo,CH; Bruder-Nascimento,A; Sugizaki,MF; Carneiro,MV; Villas Boas,PJF. |
| Yeasts are becoming a common cause of nosocomial fungal infections in immunocompromised patients. Such infections often develop into sepsis with high mortality rates. The aim of this study was to evaluate some of the numerous factors associated with the development of candidemia. Medical records were retrospectively analyzed of 98 Candida spp. patients. Results showed that the most prevalent risk factors for developing candidemia were: antibiotics and antifungal agents (93.9% and 79.6%, respectively); the use of central venous catheter (93.9%); mechanical ventilation (73.5%); and parenteral nutrition (60.2%). The main species of Candida found were: C. parapsilosis (37.76%), C. albicans (33.67%); and others (28.57%). C. glabrata showed the highest mortality... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candidemia; Mortality; Associated factors; Candida albicans. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000200015 |
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| Inácio, Marielle Cascaes; Paz, Tiago Antunes; Bertoni, Bianca Waléria; Pereira, Ana Maria Soares. |
| Cochlospermum regium (Bixaceae) is a medicinal plant species native to the Brazilian savannah, known as the Cerrado. Local communities use its roots to treat infections of the female reproductive system. This study evaluated how seasonality, phenological stage, geographical location, plant age, and plant cultivation substrate affect the antimicrobial activity of Cochlospermum regium roots against Candida albicans. Although the plant displayed antimicrobial action in all the assayed conditions, the roots collected during fall and winter inhibited C. albicans the most effectively. The geographical location in which the plant material was found did not influence its biological response. Plant age and cultivation substrate did impact the biological response;... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 5.01.03.00-8 Bixaceae; STAMP (Screening Test for Antibiotics in Medicinal Plants); Candida albicans; Cerrado; Algodãozinho-do-campo. Fitotecnia. |
| Ano: 2016 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAgron/article/view/30567 |
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| FABRI,RODRIGO L.; SÁ,DANIEL S. DE; PEREIRA,ANA PATRÍCIA O.; SCIO,ELITA; PIMENTA,DANIEL S.; CHEDIER,LUCIANA M.. |
| Manihot multifida (L.) Crantz (Euphorbiaceae) is widely used in popular medicine for the treatment of infected wounds. This study evaluated thein vitro antioxidant and antimicrobial potential of this species against strains of Gram-positive and Gram-negative bacteria and fungi, known to cause infections in humans. The extracts showed minimal inhibitory concentration (MIC) varying from 39 to 2500 µg/mL for antimicrobial activity. The methanolic extract of fruits, aqueous and hexane extracts of leaves showed a very strong activity against Candida albicans(ATCC 18804) with MIC of 39 µg/mL. Furthermore, the methanolic extract of M. multifida leaves exhibited DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging potential with inhibitory concentration (IC50) values... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial; Antioxidant; Candida albicans; Cytotoxicity; Manihot multifida. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100303 |
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| Souza,W.A.; Siqueira,A.M.. |
| Foram realizadas a identificação e a sorotipagem de C. albicans isoladas de fezes de bovinos em amamentação natural. Para o isolamento, utilizou-se o meio seletivo e diferencial de Pagano Levin, adicionado de bifenilo na concentração final de 0,1%. De 210 bovinos inicialmente considerados, 70 adultos, 68 bezerros após o desmame e 72 bezerros em fase de amamentação natural, observou-se positividade para C. albicans somente em nove amostras de fezes de bezerros em fase de amamentação (12,5%). A determinação do sorotipo por meio de provas de aglutinação direta em lâmina, com soros monoespecíficos, revelou que a totalidade das amostras isoladas pertencia ao sorotipo A. O bifenilo na concentração de 0,1% mostrou-se inibitório para a maioria dos bolores sem,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bovino; Candida albicans; Candidíase; Sorotipos. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000300003 |
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| Jiangfan,Xiu; Tao,Wang; Yu,Wang; Jianwei,Wu; Guo,Guo; Yingchun,Zhang; Xiaoli,Shang. |
| ABSTRACT Housefly, Musca domestica, has a complicated immune system. However, its underlying operating mechanism remains elusive. Candida albicans is a major pathogen affecting humans by causing deep infection fungous disease, but it is non-symbiotic in houseflies. To investigate the C. albicans infection process in housefly, the changes in morphological and histological and expression patterns of antimicrobial peptide were monitored to indicate the insect's response to fungal infection. The results showed that scattered brown spots were comprising melanized encapsulation and encapsulated fungal cells were initially observed at the inner side of larvae's body wall 3 h post-infection (PI). Between 6 and 36 h PI, the whole body of larvae was densely covered... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Musca domestica; Larvae; Candida albicans; Infection; Innate immunity. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100340 |
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| Das,Gitishree; Patra,Jayanta Kumar; Choi,Jaehyuk; Baek,Kwang-Hyun. |
| ABSTRACT Equisetum arvense, a fern species possesses a number of pharmaceutical prospective. In the present study, a total of 103 endophytic bacteria isolated from E. arvense and were evaluated for their anticandidal property against five Candida species, two C. albicans, C. glabrata, C. saitoana and C. geochares. Out of them fifty one were identified as per the morphological and molecular characterisation using 16S rRNA gene sequencing and among them, ten promising endophytic bacteria were mentioned in the present study. Among ten endophytic bacteria, Psychrobacillus insolitus and Curtobacterium oceanosedimentum exerted highest anticandidal effect against C. albicans KACC 30062 and C. glabrata KBNO6P00368, with diameter of inhibition zones of 21.30±0.41... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anticandidal effect; Endophytic bacteria; Equisetum arvense; Candida albicans; Candida glabrata. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100455 |
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| Giraldo,Paulo C.; Gonçalves,Ana Katherine; Eleutério Junior,José. |
| The genital mechanisms of defense are not well understood and are therefore ignored during therapy. This fact results in a great number of cases of treatment failure. The mucosa is an important protective factor of the genital female system, through self-defense mechanisms, and secretor antibodies (immunoglobulin A). The lymphoid tissue exerts protective anti-inflammatory activity, besides inhibiting microorganism adherence, neutralizes viruses and toxins and stabilizes the mucosal flora. Although certain microorganisms, such as viruses and fungus, are controlled by cellular immunity, secretory IgA can also exert an important role in the control of these agents. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vaginal immunity; Genital infections; HPV; Candida albicans; Secretory IgA. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400002 |
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| Shinde,Ravikumar Bapurao; Raut,Jayant Shankar; Chauhan,Nitin Mahendra; Karuppayil,Sankunny Mohan. |
| Biofilms formed by Candida albicans, a human pathogen, are known to be resistant to different antifungal agents. Novel strategies to combat the biofilm associated Candida infections like multiple drug therapy are being explored. In this study, potential of chloroquine to be a partner drug in combination with four antifungal agents, namely fluconazole, voriconazole, amphotericin B, and caspofungin, was explored against biofilms of C. albicans. Activity of various concentrations of chloroquine in combination with a particular antifungal drug was analyzed in a checkerboard format. Growth of biofilm in presence of drugs was analyzed by XTT-assay, in terms of relative metabolic activity compared to that of drug free control. Results obtained by XTT-metabolic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antifungal; Biofilm; Candida albicans; Combination; Chloroquine; Drug resistance. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000400002 |
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| Braga-Silva,L.A.; Mesquita,D.G.A.; Ribeiro,M.D.; Carvalho,S.M.F.; Fracalanzza,S.E.L.; Santos,A.L.S.. |
| Candida albicans is an opportunistic fungal pathogen that causes severe systemic infections in immunosuppressed individuals. C. albicans resistance to antifungal drugs is a severe problem in patients receiving prolonged therapy. Moreover, trailing yeast growth, which is defined as a resistant MIC after 48 h of incubation with triazole antifungal agents but a susceptible MIC after 24 h, has been noted in tests of antifungal susceptibility against some C. albicans isolates. In this context, we recently noticed this phenomenon in our routine susceptibility tests with fluconazole/itraconazole and C. albicans clinical isolates. In the present study, we investigated the production of cell-associated and secreted aspartyl peptidases (Saps) in six trailing... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida albicans; Trailing growth; Secreted aspartyl peptidases; Sap2. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000800013 |
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| Chaves,Guilherme M.; Cavalcanti,Maria Auxiliadora de Q.; Carneiro-Leão,Ana Maria dos A.; Lopes,Silvia L.. |
| With the purpose to evaluate Candida albicans virulence in vivo, two strains selected were based on their phospholipase and proteinase activity, and used in a model of experimental infection. One strain, isolated from vaginal secretion, was stocked at the URM Culture Collection for 43 years and presented high phospholipase (Pz=0.217) and proteinase (1.386 U.mL-1) activity. The other strain was a fresh strain isolated from oropharyngeal secretion of an AIDS patient, and presented low phospholipase (Pz=0.482) and proteinase (0.780 U.mL-1) activity. The strains were inoculated via intraperitoneum in immunosuppressed and non-immunosuppressed mice (Mus musculus) and the infection was evaluated over a period of 21 days. Liver, spleen, lungs and kidneys were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida albicans; Extracellular enzymes; Virulence; Experimental infection. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822004000300010 |
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| Mardegan,Rita de Cássia; Klein,Marlise Inêz; Golvea,Magda Baglione; Rodrigues,Janaina Aparecida Oliveira; Gonçalves,Reginaldo Bruno; Höfling,José Francisco. |
| Candida albicans oral strains collected from caries-free and caries-active healthy children ranging from 24 to 36 months old, were studied. The aim of the study was to determine proteinase and phospholipase activities produced by Candida albicans in the two groups and to determine the phenotypic diversity of these enzymes based on genetic polymorphism using the AP-PCR method. Strains identified by morphological and fermentation tests as C. albicans were grown in proteinase and phospholipase agar media at 37ºC for 7 and 4 days, respectively. After the incubation period, the enzyme activity of the proteinase and phospholipase positive strains was measured. All strains were subjected to AP-PCR, using the arbitrary primer AP-3. The enzymatic analysis showed no... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida albicans; Genotyping; Proteinase; Phospholipase; Virulence. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822006000100005 |
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| Registros recuperados: 42 | |
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