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| Registros recuperados: 42 | |
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| Borges,Kleiton Silva; Brassesco,María Sol; Scrideli,Carlos Alberto; Soares,Ademilson Espencer Egea; Tone,Luiz Gonzaga. |
| Propolis is a resin formed by a complex chemical composition of substances that bees collect from plants. Since ancient times, propolis has been used in folk medicine, due to its biological properties, that include antimicrobial, anti-inflammatory, antitumoral and immunomodulatory activities. Glioblastoma is the most common human brain tumor. Despite the improvements in GBM standard treatment, patients' prognosis is still very poor. The aim of this work was to evaluate in vitro the Tubi-bee propolis effects on human glioblastoma (U251 and U343) and fibroblast (MRC-5) cell lines. Proliferation, clonogenic capacity and apoptosis were analyzed after treatment with 1 mg/mL and 2 mg/mL propolis concentrations for different time periods. Additionally,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Glioblastoma; Propolis; Temozolomide; U251; U343. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000200024 |
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| Almansour,Mansour; Jarrar,Yazun; Jarrar,Bashir. |
| Sildenafil is widely used for the treatment of erectile dysfunction with few studies are available on the protective role of propolis against its reproductive toxicity. The present study aims to investigate the hormonal biochemical and histomorphometric alterations induced in the testicular tissues by sildenafil overdoses. Four groups of rabbits were exposed to sildenafil with or without propolis as follows: Group I received the formulated vehicle, Group II received sildenafil (3 mg/kg), Group III received propolis (50 mg/kg), Group IV received sildenafil plus propolis. Sildenafil lowered body weight gain, testosterone and follicular stimulating hormone concentration but increased testis index while luteinizing hormone was almost not affected. Moreover,... |
| Tipo: Journal article |
Palavras-chave: Propolis; Sildenafil; Testis; Histological alterations; Toxicity. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000200020 |
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| Pereira-Filho,Rose Nely; Batista,Fellipe Santos; Ribeiro,Danielle Rodrigues; Melo,Genecy Calado de; Reis,Francisco Prado; Melo,Allan Ulisses Carvalho de; Gomes,Margarete Zanardo; Cardoso,Juliana Cordeiro; Albuquerque Júnior,Ricardo Luiz Cavalcanti de. |
| The aim of this study was to assess the effect of oral administration of Hydroalcoholic Extract of Green Propolis (HEGP) on dermal carcinogenesis in rodent model. For the biological assay, we used 36 mice, assigned into 6 groups (n=6): CTR (treated with 100 mg/kg HEGP and no tumor induction), TUM (treated with water and tumor induction), GP10 (treated with 10 mg/kg HEGP and tumor induction), GP50 (treated with 50 mg/kg HEGP and tumor induction) and GP100 (treated with 100 mg/kg HEGP and tumor induction). Cancer induction was performed in the back of the mice by topical application of DMBA. After 16 weeks, mice were euthanized and their backs were submitted to post-mortem histological analysis. The mean number of lesions developed in TUM (4.14±0.89) was... |
| Tipo: Journal article |
Palavras-chave: Propolis; Skin cancer. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000200024 |
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| Albuquerque-Júnior,Ricardo Luiz Cavalcanti de; Barreto,André Luiz Santos; Pires,Jônatas Almeida; Reis,Francisco Prado; Lima,Sônia Oliveira; Ribeiro,Maria Amália Gonzaga; Cardoso,Juliana Cordeiro. |
| Propolis, an apitherapic product widely employed in natural medicine, presents various biological properties, such as bactericidal and anti-inflammatory activities, but only few reports have looked at the Brazilian red propolis variety. Collagen films have been employed to improve wound healing and some studies have investigated the effect of natural products incorporated into these films. Thus, the aim of this study was to analyze the effect of collagen-based films containing red propolis on wound healing. Therefore, wounds performed in the back of rats were dressed with collagen-based films (G2), and collagen-based films containing red propolis (G3); undressed worked as control (G1). After 3, 7 and 14 days the animals were euthanized, and the wounds were... |
| Tipo: Journal article |
Palavras-chave: Propolis; Wound healing; Occlusive dressings; Type-I collagen. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400025 |
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| SFORCIN,J.M.; FUNARI,S.R.C.; NOVELLI,E.L.B.. |
| Ethanolic extracts of the bee glue, a resinous substance collected by honeybees called propolis, have been widely used in folk medicine since ancient times. Antibacterial, antifungal and thus antiseptic properties may represent the basis for the historical and present use of these extracts in dermatology, against inflammatory conditions and common colds. This work was carried out in order to verify possible biochemical alterations in some seric parameters of propolis-treated rats. It was shown that propolis possesses an antioxidant property and its administration did not affect either amylase and alanine transaminase activities or total protein concentration. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propolis; Serum; Biochemistry. |
| Ano: 1995 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301995000100005 |
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| SFORCIN,J. M.; FERNANDES JÚNIOR,A.; LOPES,C. A. M.; FUNARI,S. R. C.; BANKOVA,V.. |
| Recently, propolis has been attracting the attention of researchers due to various biological activities and therapeutic properties. In Brazil, propolis is produced all year long, so there may be some seasonal variations. This work was carried out in order to compare propolis collected during the four seasons by its in vitro antimicrobial activity on yeast pathogens isolated from human infections. Propolis was produced by africanized honeybees in Botucatu, São Paulo State, collected throughout a year and pooled by season. Hydroalcoholic solutions of propolis were prepared with each pool and diluted in agar, using serial concentrations of propolis from each pool. A determination of minimal inhibitory concentration (MIC) was performed. The results show that... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propolis; Season; Candida; Antimicrobial activity. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302001000100009 |
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| ORSI,R.O.; FUNARI,S.R.C.; SOARES,A.M.V.C.; CALVI,S.A.; OLIVEIRA,S.L.; SFORCIN,J.M.; BANKOVA,V.. |
| Propolis has been the subject of several recent studies, with the aim of elucidating its biological and pharmacological properties. Propolis has a well-known antimicrobial activity as well as antioxidant, antitumoral, antiinflammatory, and regenerative properties, but literature about its effects on the immune response is scarce. The goal of this work was to evaluate the propolis effect on macrophage activation by oxygen (H2O2) and nitrogen (NO) metabolite determination. Propolis was produced by africanized honeybees and hydroalcoholic solutions were prepared at different concentrations. Peritoneal macrophages were obtained from male BALB/c mice and culture cells were stimulated in vitro with propolis or interferon-gamma (IFN-gamma). In the in vivo assay,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propolis; Macrophages; Hydrogen peroxide; Nitric oxide. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200006 |
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| FERNANDES Jr.,A.; SUGIZAKI,M.F.; FOGO,M.L.; FUNARI,S.R.C.; LOPES,C.A.M.. |
| The in vitro activity of propolis against 118 Staphylococcus aureus, 108 Escherichia coli, 60 Salmonella typhimurium, 50 Candida albicans, 23 Candida parapsilosis, 19 Candida tropicalis and 14 Candida guilliermondii isolated from human infections was studied by the agar dilution method. Among the bacteria, the Gram-negative were the least susceptible organisms showing minimal inhibitory concentration (MIC) for 90% of the strains tested ranging from 22.5 mg/ml - 10,2% V/V to 23.1 mg/ml - 10.5% V/V. The MIC's for Candida ranged from 0.80 mg/ml to > 11 mg/ml (0.40% V/V to > 5.0% V/V), the strains of C. parapsilosis being the least susceptible. The relative order of susceptibility among all isolates, was: S.aureus > C. tropicalis >... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propolis; Antimicrobial activity; Bacteria; Yeast pathogens; Candida sp. |
| Ano: 1995 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301995000200003 |
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| SFORCIN,J. M.; NOVELLI,E. L. B.; FUNARI,S. R. C.. |
| Propolis has been the subject of recent scientific investigation due to its biological properties, such as antibiotic, antiinflammatory, anesthetic, healing, immunomodulatory, antioxidant, and carcinostatic. The purpose of this study was to analyze the biochemical profile of propolis-treated rats to observe whether propolis might lead to side effects after administration. Evaluation of total protein, glucose, urea, creatinine, triglycerides, cholesterol, and HDL-cholesterol concentrations and determination of aminotransferases (AST and ALT) and lactic dehydrogenase (LDH) in propolis-treated rat serum were performed. The seasonal effect on propolis activity was also analyzed, considering the biochemical variables evaluated. The lack of clinically important... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propolis; Season; Biochemistry; Serum. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000200005 |
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| Muli,E. M.; Maingi,J. M.. |
| The present study aimed at investigating the susceptibility of the microorganisms Pseudomonas aeruginosa, Salmonella typhi, Escherichia coli, Staphylococcus aureus, and Bacillus subtilis to ethanolic extracts of propolis (EEP) from three regions of Kenya (Taita, Tana and Samburu). Propolis was extracted using four different concentrations of ethanol: pure, 70%, 50%, and 30%. Ethanol (70%) and Streptomycin were used as controls. The agar diffusion method using filter paper disks was employed. Antibacterial activity was determined as an equivalent of the inhibition zones diameters (in millimeters) after incubation at 37°C for 24h. Significant differences in the antibacterial activities of propolis were observed among the three regions, depending on the test... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Apis mellifera; Propolis; Antibacterial agents; Disk diffusion antimicrobial tests. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000300008 |
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| Orsi,R. O.; Sforcin,J. M.; Funari,S. R. C.; Gomes,J. C.. |
| The direct effect of ethanolic extract of propolis on guinea pig lung cell suspension containing mast cells, as well as its influence on the histamine release induced by antigen (ovoalbumin 10 mug/ml) and ionophore A 23187 (3 muM) were investigated. Propolis ethanolic extract (300 mug/ml) increased the histamine release in guinea pig lung suspension containing mast cells by a cytotoxic effect. Lower concentrations of propolis had no effect on histamine release. Our results demonstrated that propolis (3, 10, 30, and 100 mug/ml) shows no significant effect on the histamine release induced by ionophore and antigen. Based on these results, we suggest that propolis could directly activate mast cells, promoting inflammatory mediators release by cytotoxic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mast cells; Allergy; Histamine; Propolis. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000100009 |
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| Orsi,R. O.; Sforcin,J. M.; Funari,S. R. C.; Fernandes-JR.,A.; Rodrigues,P.; Bankova,V.. |
| Propolis shows biological properties such as antibacterial action. This bee product has a complex chemical composition, which depends on the local flora where it is produced. Salmonella serovars are responsible for human diseases that range from localized gastroenteritis to systemic infections. The aim of the present study was to investigate the susceptibility of Salmonella strains, isolated from food and infectious processes, to the antibacterial action of Brazilian and Bulgarian propolis, as well as to determine the behavior of these bacteria, according to the incubation period, in medium plus propolis. Dilution of ethanolic extract of propolis in agar was the used method. Brazilian and Bulgarian propolis showed an antibacterial action against all... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propolis; Susceptibility profile; Salmonella; Food; Infection. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000400006 |
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| Orsi,R. O.; Sforcin,J. M.; Rall,V. L. M.; Funari,S. R. C.; Barbosa,Luciano; Fernandes,JR A.. |
| Propolis antibiotic action has been widely investigated. This assay was carried out in order to observe the in vitro antibacterial activity of propolis against Salmonella enteritidis isolated from food and Salmonella typhimurium isolated from human infections. Propolis was collected by Apis mellifera in two regions of Brazil (Mossoró, Rio Grande do Norte State; and Urubici, Santa Catarina State). Both strains survival percentage decreased with time of incubation in Ethanolic Extracts of Propolis (EEP), demonstrating bactericidal effect after 24 hours. It was also observed that EEP from Mossoró was more effective than that from Urubici. The control of the propolis solvent - 70% ethanol - was less effective than EEP, showing only a bacteriostatic effect. We... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propolis; Susceptibility profile; Salmonella; Food; Infection. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000200003 |
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| Ferreira,Daiane; Unfer,Taís Cristina; Rocha,Hélio Carlos; Kreutz,Luiz Carlos; Koakoski,Gessi; Barcellos,Leonardo José Gil. |
| An experiment was conducted to evaluate the potential of honey, propolis, and bee pollen for the reversal of lipid peroxidation induced by tebuconazole (TEB) in South American catfish (Rhamdia quelen), in which the concentration of thiobarbituric acid reactive substances (TBARS), the activity of the antioxidant enzyme glutathione-S-transferase (GST) and the concentrations of non-enzymatic antioxidants, reduced glutathione (GSH), ascorbic acid, and non-protein thiols were assessed. Honey (0.125 g L-1) and bee pollen (0.05 g L-1) added to the water reverse the production of TBARS induced by TEB, while propolis demonstrated a pro-oxidant effect, inducing an increase in TBARS production. The data presented herein suggest that the addition of water to honey and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Bee pollen; Honey; Lipid peroxidation; Propolis; Tebuconazole. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-62252012000100021 |
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| Montenegro,G; Mujica,AM; Peña,RC; Gómez,M; Serey,I; Timmermann,BN. |
| Correspondence analysis allows identifying various kinds of propolis due to botanical source. The first site, Colliguay is identified by a higher content of pollen of Escallonia pulverulenta, and Nothofagus dombeyi. Two other very close sites are La Vacada and Quilaco, where pollen of Mentha pulegium, besides Echium, Cichorium, and Luma are frequently identified. Other groups including various contents of pollen of Eucalyptus, Salix or Prunus and other native resources such as Peumus, Cryptocarya and Quillaja are not well defined. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propolis; Botanical source; Mediterranean type climate; Analysis of correspondence. |
| Ano: 2004 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-56572004000100018 |
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| Registros recuperados: 42 | |
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