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131I-induced changes in rat thyroid gland function BJMBR
Torlak,V.; Zemunik,T.; Modun,D.; Capkun,V.; Pesutic-Pisac,V.; Markotic,A.; Pavela-Vrancic,M.; Stanicic,A..
Therapeutic doses of 131I administered to thyrotoxic patients may cause thyroid failure. The present study used a rat model to determine thyroid function after the administration of different doses of 131I (64-277 µCi). Thirty male Fisher rats in the experimental group and 30 in the control group (untreated) were followed for 6 months. The animals were 4 months old at the beginning of the experiment and were sacrificed at an age of 9 months. Hormone concentration was determined before 131I administration (4-month-old animals) and three times following 131I administration, when the animals were 7, 8, and 9 months old. The thyroid glands were removed and weighed, their volume was determined and histopathological examination was performed at the end of the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Thyroid gland; 131I; Hormones; Histopathology; T3; T4; TSH.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800009
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Alternative complement pathway and factor B activities in rats with altered blood levels of thyroid hormone BJMBR
Bitencourt,C.S.; Duarte,C.G.; Azzolini,A.E.C.S.; Assis-Pandochi,A.I..
Evaluating the activity of the complement system under conditions of altered thyroid hormone levels might help elucidate the role of complement in triggering autoimmune processes. Here, we investigated alternative pathway (AP) activity in male Wistar rats (180 ± 10 g) after altering their thyroid hormone levels by treatment with triiodothyronine (T3), propylthiouracil (PTU) or thyroidectomy. T3 and thyroxine (T4) levels were determined by chemiluminescence assays. Hemolytic assays were performed to evaluate the lytic activity of the AP. Factor B activity was evaluated using factor B-deficient serum. An anti-human factor B antibody was used to measure factor B levels in serum by radial immunodiffusion. T3 measurements in thyroidectomized animals or animals...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Thyroid hormone; Complement system; Alternative complement pathway; Factor B; T3; T4.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300006
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周産期の未経産牛と新生子牛の甲状腺機能に対する硝酸塩の影響 OAK
平本, 典子; 大谷, 昌之; 田辺, 茂之; 宇塚, 雄次; 更科, 孝夫; HIRAMOTO, Noriko; OHTANI, Masayuki; TANABE, Shigeyuki; UZUKA, Yuji; SARASHINA, Takao.
Palavras-chave: 子牛; 未経産牛; 硝酸ナトリウム; T4; T3; Calf; Heifer; Sodium nitrate.
Ano: 2001 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/1249
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Physiological and biochemical response to Omega-3 plus as a dietary supplement to growing goats under hot summer conditions R. Bras. Zootec.
Teama,Fatma Edrees Ibrahim; El-Tarabany,Akram A..
ABSTRACT The objective of the present study was to assess the effect of dietary supplementation of Omega-3 plus on some the physiological and biochemical traits in growing Baladi goats under hot summer conditions. Thirty-four growing male goats (4-5 months old) were randomly divided into two equal groups. Animals in group 1 were fed a concentrate feed mixture (CFM), which was the control group. Goats in group 2 (the experimental group) were offered Omega-3 plus (1,000 mg/animal day-1) (30% fish oil, containing 18% eicosapentaenoic acid and 12% docosahexaenoic acid + 100 mg wheat germ oil (0.22% tocopherols)) daily in addition to the basal diet for four months (the experimental period) during the hot summer season. Body weight (BW) changes of both groups...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cholesterol; Heat stress; IgG; Liver enzymes; T3; T4.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982016000400174
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