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| Registros recuperados: 195 | |
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| Different levels of insulin sensitivity have been described in several animal models of obesity as well as in humans. Monosodium glutamate (MSG)-obese mice were considered not to be insulin resistant from data obtained in oral glucose tolerance tests. To reevaluate insulin resistance by the intravenous glucose tolerance test (IVGTT) and by the clamp technique, newborn male Wistar rats (N = 20) were injected 5 times, every other day, with 4 g/kg MSG (N = 10) or saline (control; N = 10) during the first 10 days of age. At 3 months, the IVGTT was performed by injecting glucose (0.75 g/kg) through the jugular vein into freely moving rats. During euglycemic clamping plasma insulin levels were increased by infusing 3 mU . kg-1 . min-1 of regular insulin until a... |
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Palavras-chave: Monosodium glutamate; Insulin resistance; Obesity; Clamp technique. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000500016 |
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| Ribeiro,M.M.; Trombetta,I.C.; Batalha,L.T.; Rondon,M.U.P.B.; Forjaz,C.L.M.; Barretto,A.C.P.; Villares,S.M.F.; Negrão,C.E.. |
| To study the relationship between the sympathetic nerve activity and hemodynamic alterations in obesity, we simultaneously measured muscle sympathetic nerve activity (MSNA), blood pressure, and forearm blood flow (FBF) in obese and lean individuals. Fifteen normotensive obese women (BMI = 32.5 ± 0.5 kg/m²) and 11 age-matched normotensive lean women (BMI = 22.7 ± 1.0 kg/m²) were studied. MSNA was evaluated directly from the peroneal nerve by microneurography, FBF was measured by venous occlusion plethysmography, and blood pressure was measured noninvasively by an autonomic blood pressure cuff. MSNA was significantly increased in obese women when compared with lean control women. Forearm vascular resistance and blood pressure were significantly higher in... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Sympathetic nerve activity; Blood pressure; Obesity. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000400006 |
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| Pardini,V.C.; Velho,G.; Reis,R.; Purisch,S.; Blanché,H.; Vieira,J.G.H.; Moisés,R.C.S.. |
| Glucokinase (GCK) is an enzyme that regulates insulin secretion, keeping glucose levels within a narrow range. Mutations in the glucokinase gene cause a rare form of diabetes called maturity-onset diabetes of the young (MODY). An early onset (less than 25 years), autosomal dominant inheritance and low insulin secretion stimulated by glucose characterize MODY patients. Specific insulin and proinsulin were measured in serum by immunofluorimetric assays (IFMA) during a 75-g oral glucose tolerance test (OGTT). Two kindreds (SA and LZ) were studied and compared to non-diabetic unrelated individuals (control group 1) matched for age and body mass index (BMI). In one kindred, some of these subjects were also obese (BMI >26 kg/m2), and other family members... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Proinsulin; Insulin; MODY; Glucokinase; Obesity. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000400008 |
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| Saleem,Zikria; Saeed,Hamid; Khan,Zohaib Abbas; Khan,Muhammad Imran Hassan; Hashmi,Furqan Khurshid; Islam,Muhammad; Bashir,Afzaal; Sadeeqa,Saleha. |
| The study was performed to estimate the association of hypertension and dyslipidaemia with increasing body weight and obesity in Type II diabetics of Lahore, Pakistan. An observational study was conducted by enrolling 2708 obese diabetics from four diabetes care centres of Lahore, Pakistan. Data was collected for a period of 7 months. Associations were estimated using chi-square, binary and multinomial logistic regression. Data suggested that blood pressure, systolic and diastolic, exhibited continual increase with increasing body weight and obesity class in diabetes patients with 41.8% increase in the prevalence of hypertension in obesity class III subjects (OR; 1.91, p=0.02). Likewise, triglycerides and total cholesterol exhibited continual increase in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Type II Diabetes Mellitus; Dyslipidaemia; Obesity; HbA1c; Lahore/Pakistan. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100503 |
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| Monteiro,Vanessa; Matioli,Graciette. |
| This study aimed to determine the anthropometric profile and diet of 652 school children from the 1st to 4th grades of elementary education in six private schools in the city of Maringá, Paraná, Brazil. Children's weight and height were classified according to the Body Mass Index proposed by Must et al. (1991). Food consumption was evaluated by means of a questionnaire about daily food frequency. Statistical analysis was carried out using linear and logistic regression tests, with a significance level of 5%. High rates of overweight and obesity, 21.9% and 13.3% respectively, were observed, which did not show a significant relationship with total food consumption. The data obtained were: high consumption of foods rich in energy, such as sugar- and fat-rich... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alimentary habits; Obesity; Body mass index; Infant nutrition. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300007 |
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| Martins,Luana Mota; Oliveira,Ana Raquel Soares; Cruz,Kyria Jayanne Clímaco; Torres-Leal,Francisco Leonardo; Marreiro,Dilina do Nascimento. |
| White adipose tissue (WAT) is considered an endocrine organ. When present in excess, WAT can influence metabolism via biologically active molecules. Following unregulated production of such molecules, adipose tissue dysfunction results, contributing to complications associated with obesity. Previous studies have implicated pro- and anti-inflammatory substances in the regulation of inflammatory response and in the development of insulin resistance. In obese individuals, pro-inflammatory molecules produced by adipose tissue contribute to the development of insulin resistance and increased risk of cardiovascular disease. On the other hand, the molecules with anti-inflammatory action, that have been associated with the improvement of insulin sensitivity, have... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Obesity; Inflammation; Adipose tissue; Adipokines; Insulin resistance. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400677 |
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| Gandarillas,Mónica; Bas,Fernando. |
| The prevalence of obesity has increased dramatically over the last 20 years. Moreover, morbid obese patients routinely suffer from serious medical problems, especially cardiovascular disease. Medical therapy for morbid obesity offers no substantial long-term benefit, and thus the first choice therapy for severe obesity is effectively surgery. Gastrointestinal surgery for obesity, also called bariatric surgery, alters the digestive process by limiting food intake and facilitating malabsorption of nutrients from the diet. This arricie reviews the types and evolution of morbid obesity surgery performed in humans and proposes the pig model as an alternative when practicing new surgical techniques or improving actual procedures, as well as to evaluate the... |
| Tipo: Journal article |
Palavras-chave: Bariatric surgery; Human obesity; Obesity; Pig nutrition; Swine nutrition. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202009000200002 |
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| Dittrich,Gustavo; Campos,Gabriela Marin Van der Broocke; Sousa,Marlos Gonçalves; Oliveira,Simone Tostes. |
| ABSTRACT: Pwave dispersion (Pd) is an electrocardiographic index defined as the difference between the minimum and maximum Pwave duration in multiple leads. The augmentation of Pd reflects the discontinuous and inhomogeneous atrial depolarization resulting from cardiac and non-cardiac conditions. In humans, an increased Pd is associated with the development of cardiac arrhythmias, particularly atrial fibrillation. To investigate Pd in obese dogs, we enrolled 76 dogs, which were classified in four distinct categories according to body condition and the existance of valve insufficiency: obese dogs (O), dogs with both obesity and cardiac disease (O+CD), lean dogs with cardiac disease (CD) and healthy controls (H). To be included in the study, all dogs... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mitral degeneration; P wave indices; Adiposity; Obesity; Left atrial size. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001000602 |
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| Araújo,Andreia Cristina Ferraz; Rocha,Juliete Castro; Paraiso,Alanna Fernandes; Ferreira,Adaliene Versiani Matos; Santos,Sergio Henrique Sousa; Pinho,Lucineia de. |
| ABSTRACT: The present study evaluated the effects of baru nut consumption on body weight, percent adiposity, amount of adipose tissue and blood levels in obese male Swiss mice. After inducing obesity by providing high-glucose diet (60 days), the mice were divided into 4 groups (7 animals per group) and were fed on a control diet (C), high-glucose diet (HG) or high-glucose diet added with baru (HGBA) or soybean oil (HGSO). Groups fed with diet HGBA had a decrease in the weight gain and glucose and triglyceride levels when compared to diet HG. Aimals fed with HG exhibited a higher proportion of epididymal and retroperitoneal adipose tissue. The inclusion of baru nut in the diet improved the control of weight gain and glucose and triglyceride levels in obese... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Obesity; Functional food; Baru nuts. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000200405 |
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| Feitosa,Mariana Lorenção; Zanini,Surama Freitas; Sousa,Dyeime Ribeiro de; Fantuzzi,Elizabeth; Carraro,Thais Consuelo Loyola; Pinto,Camila Alves; Bertonceli,Raul Monteiro; Colnago,Geraldo Luiz. |
| ABSTRACT: Among the health disorders caused by obesity in dogs stand out hyperglycemia and hyperlipidemia. Glycemic responses are directly related to the amount and type of starch. Thus, this study aimed to evaluate the effect of different sources of starch on glycemic and lipid levels in obese dogs. These dogs were distributed in a completely randomized design in a factorial 3x2x2 (three sources starchy - corn (60%), sorghum (60%) and corn: sorghum (30:30%), two breeds - Beagle and Dachshund and males and females. After 28 days of experiment, dogs fed with corn had higher amounts of glucose (93.79A mg dL-1) (P<0.05) compared with diets containing sorghum (88.00Bmg dL-1) and corn: sorghum (88.75B mg dL-1) (P>0.05). Thus, dogs that consumed corn had a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Blood glucose; Lipid profile; Obesity; Canine. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016001202189 |
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| Freitas,Vanessa Danielle de; Castilho,Alessandra Ramos; Conceição,Luciana Auxiliadora Viebrantz da; Sousa,Valéria Régia Franco; Mendonça,Adriane Jorge; Silva,Felipe Gomes da; Almeida,Arleana do Bom Parto Ferreira de. |
| ABSTRACT: Obesity has been increasing in cats andis associated with metabolic and cardiovascular diseases. The association of these alterations can trigger the onset of metabolic syndrome (MS). Therefore, this study aimed to analyze the serum levels of glucose, fructosamine, cholesterol, triglycerides, high-density lipoprotein, low-density lipoprotein, very low-density lipoprotein (VLDL), andalanine aminotransferase of cats and to identify the possibility of MS,as well as to evaluate changes in arterial pressure. Thirty-seven cats were classified by ECC and morphometric measurements, namely, 15 obese, 12 overweight, and 10 controls. Nocat manifested MS. Only VLDL had a statistically significant difference (P<0.05) between groups. Therefore, obesity may... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Obesity; Cats hypertension dyslipidemia. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000100602 |
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| Schumacher,Bianca de Oliveira; Preuss,Edcarlos Maurino; Vargas,Carolina Galarza; Helbig,Elizabete. |
| ABSTRACT: This study aimed to evaluate the influence of replacing soybean oil with extra virgin coconut oil in normolipidic and hyperlipidic diets, on the lipid metabolism of Wistar rats. In the first stage of the experiment (30 days), 36 rats were divided into 2 groups and fed with a control or a hyperlipidic diet. Six animals from each group were then killed, and the remaining rats were redistributed into 4 new groups: 2 groups remained on the control and hyperlipidic diets, and in the diets of the other 2 groups, the soybean oil was replaced with coconut oil (30 days). At the end of the assay, the biological models were decapitated for blood collection and removal of organs and peritoneal fat. Although the diet intake differed among groups during both... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cocos nucifera L; Extra virgin coconut oil; Obesity; Rat; Diet. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016001001818 |
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| Registros recuperados: 195 | |
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