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| Registros recuperados: 221 | |
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| Paolo Tieri; Alberto Termanini; Elena Bellavista; Stefano Salvioli; Claudio Franceschi. |
| One of the phenomena observed in human aging is the progressive increase of a systemic inflammatory state, a condition referred to as “inflammaging”, negatively correlated with longevity. The five components of the Nuclear Factor kB (NF-kB) family are prominent mediators of inflammation. Several different signaling pathways activated by very diverse stimuli converge on NF-kB, resulting in a regulatory system characterized by high complexity. It is increasingly recognized that the number of components that impinges upon phenotypic outcomes of signal transduction pathways may be higher than those taken into consideration from canonical pathway representations. Scope of this analysis is to provide a wider, systemic picture of such... |
| Tipo: Poster |
Palavras-chave: Genetics & Genomics; Immunology; Bioinformatics. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/5266/version/1 |
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| Nobuoki Eshima; Minoru Tabata; Yasunori Higuchi; Shigeru Karukaya. |
| Human T-cell leukemia virus type I (HTLV-I) is a retrovirus that causes adult T-cell leukemia. The male-to-female transmission is stronger than the reverse, so the carrier proportion of women is greater than that of men. On the other hand, since the mother-to-child transmission route via the breast-feeding is common for baby boys and girls, it has been thought the HTLV-I proportions of boys and girls are the same until now. A question arises as to whether the "innate protection powers against human virus" are the same between baby boys and girls. We utilize Blood donors in 1995-1998, which were provided by Japan Red Cross Society of Oita, Japan. The data are summarized into the frequency table with respect to gender and age. The age... |
| Tipo: Manuscript |
Palavras-chave: Cancer; Immunology; Microbiology. |
| Ano: 2008 |
URL: http://precedings.nature.com/documents/1987/version/1 |
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| Wan-Chung(Wan-Jiung) Hu; August Louis Bourgeois; Nathan Wolfe; Sher Singh; Anne Jedlicka; Alan Scott. |
| Using microarray analysis, we showed up-regulation of Toll-like receptors 1,2,4,7,8, NF-[kappa][BETA], TNF-[alpha], p38-MAPK and MHC molecules in human peripheral blood mononuclear cells following infection with Plasmodium falciparum. We report herein further studies based on time-course microarray analysis with a focus on malaria-induced host immunity. Results show that in early malaria; selected immunity-related genes were up-regulated including alpha, beta, and gamma interferon related genes, as well as genes of IL-15, CD36, chemokines (CXCL10, CCL2, S100A8/9, CXCL9, and CXCL11), TRAIL and IgG Fc receptors. During acute febrile malaria, up-regulated genes included alpha, beta, and gamma interferon related genes, IL-8, IL-1[beta], IL-10 downstream... |
| Tipo: Manuscript |
Palavras-chave: Genetics & Genomics; Immunology; Microbiology; Bioinformatics. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/5930/version/1 |
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| Massó, J.A.. |
| Todos los organismos multicelulares son susceptibles a enfermedades, por lo que estos han desarrollado sistemas de defensa contra los organismos patógenos, y los peces no han sido la excepción. Su sistema inmune al igual que el resto de los vertebrados puede dividirse en dos tipos: el sistema inmune adaptativo y el sistema inmune innato. Ambos poseen componentes celulares y humorales. Dentro de los componentes humorales del sistema inmune innato se encuentran los péptidos antimicrobianos (AMPs), los cuales son típicamente de 12-50 aminoácidos con una carga neta positiva de +2 a +7. Debido a que los AMPs pueden desplegar una actividad de amplio espectro contra una gran variedad de patógenos y algunas células cancerosas, el interés de estos ha aumentado... |
| Tipo: Theses and Dissertations |
Palavras-chave: Immunology; Marine fish; Immunology; Http://aims.fao.org/aos/agrovoc/c_3808. |
| Ano: 2010 |
URL: http://hdl.handle.net/1834/3589 |
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| Soliman, M.K.; Mohamed, S.G.; El-Gohary, M.S.; Khalil, R.H.; El-Banna, S.. |
| The effect of metrifonate on the immunity of the exposed fish are evaluated through the determination of the antibody titer and mortality rate during the challenge trial. In the chronic toxic exposure to metrifonate by dose 0.17mg/liter for 8 weeks, the more clear signs were darkness of fish color with hemorrhagic patches & loosing of scale at end of the trial the color return to normal. Determination of some blood parameters revealed significant decrease of white blood cell count, as there were lymphopenia and nueutrophilia during the chronic exposure to metrifonate. Phagocytic assay revealed a significant decrease in both phagocytic activity (PA) and phagocytic index(PI).Hypoproteinami hypoglobulinaemia and hypoalbuminaemia were observed. The... |
| Tipo: Journal Contribution |
Palavras-chave: Biology; Immunology; Biology; Http://aims.fao.org/aos/agrovoc/c_925. |
| Ano: 2005 |
URL: http://hdl.handle.net/1834/1218 |
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| Ndong, D.; Chen, Yu Yuan; Lin, Yu Hung; Baskaralingam, V.; Chen, Jiann Chu. |
| Mozambique tilapia Oreochromis mossambicus acclimated to 27 °C were then held at 19, 23, 27 (control), 31 and 35 °C, and were examined for non-specific cellular and humoral responses after 12–96 h. Total leucocyte count decreased significantly when fish were transferred to 19 and 23 °C after 48 and 96 h, and when transferred to 35 °C over 12–96 h, respectively. Respiratory burst decreased significantly when fish were transferred to 19, 31 and 35 °C over 24–96 h, whereas phagocytic activity and phagocytic index decreased significantly when fish were transferred to low temperatures (19 and 23 °C) and high temperatures (31 and 35 °C) over 12–96 h. Lysozyme activity decreased significantly when fish were transferred to 19 °C after 12–96 h, but increased... |
| Tipo: Journal Contribution |
Palavras-chave: Immunology; Fish culture; Fish diseases; Temperature effects; Aquaculture; Biological stress; Immunology; Fish culture; Aquaculture; Fish diseases; Http://aims.fao.org/aos/agrovoc/c_3808; Http://aims.fao.org/aos/agrovoc/c_2918; Http://aims.fao.org/aos/agrovoc/c_550; Http://aims.fao.org/aos/agrovoc/c_2920. |
| Ano: 2006 |
URL: http://hdl.handle.net/1834/2614 |
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| Ferronato,Bruno O.; Merchant,Mark E.; Marques,Thiago S.; Verdade,Luciano M.. |
| The innate immune activity of the freshwater turtle Phrynops geoffroanus (Schweigger, 1812) was investigated, using a sheep-red-blood cell hemolysis assay. The time- and concentration-dependent hemolytic activity of the turtle plasma was low compared to that reported for other reptiles. However the plasma of P. geoffroanus exhibited higher activity at elevated temperatures, resulting in temperature-dependent hemolysis. The sensitivity of turtle plasma to temperature could be interpreted as a mechanism by which freshwater turtles use basking behavior to elevate body temperature, thus enhancing the innate immune response. However, we cannot discard the possibility that environmental contaminants could be affecting the turtle's immune response, since the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chelonian; Immunology; Plasma. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-46702009000400020 |
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| Buglione, Celso Carlos; UFSC; Vieira, Felipe do Nascimento; UFSC; Mouriño, José Luiz Pedreira; UFSC; Pedrotti, Fabiola Santiago; UFSC; Jatoba, Adolfo; UFSC; Martins, Maurício Laterça; UFSC. |
| This study evaluated the pathogenic characteristics of bacteria isolated from Litopenaeus vannamei during an outbreak at the Laboratory of Marine Shrimp, UFSC, Santa Catarina State, Brazil. Their virulence potential in larvae and juvenile shrimp and the effects on the total haemocyte count, phenoloxidase activity and serum agglutinate titre were examined after experimental infection. Bacterial strains were isolated from larvae and adult shrimps, identified by the AP120E biochemical system as: two strains of Vibrio alginolyticus, three of Aeromonas salmonicida and one of Pasteurella multocida sp. and Pasteurella sp. All the bacterial strains isolated in this study caused mortality in shrimp. One strain of V. alginolyticus was responsible for 97.3 and 88.7%... |
| Tipo: Resistencia a infecção |
Palavras-chave: 2.12.01.02-1 Shrimp; Experimental infection; Vibrio; Virulence; Immunology bacteriologia Shrimp; Experimental infection; Vibrio; Virulence; Immunology. |
| Ano: 2010 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/5471 |
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| ORSI,RICARDO O.; SANTOS,VIVIAN G. DOS; PEZZATO,LUIZ E.; CARVALHO,PEDRO L.P.F. DE; TEIXEIRA,CAROLINE P.; FREITAS,JAKELINE M.A.; PADOVANI,CARLOS R.; SARTORI,MARIA M.P.; BARROS,MARGARIDA M.. |
| ABSTRACT The effect of the ethanolic extract of propolis (EEP) on Aeromonas hydrophila was analyzed by determination of minimum inhibitory concentration (MIC). Then, the effects of crude propolis powder (CPP) on growth, hemato-immune parameters of the Nile tilapia, as well as its effects on resistance to A. hydrophila challenge were investigated. The CPP (0.5, 1.0, 1.5, 2.0, 2.5 and 3.0%) was added to the diet of 280 Nile tilapia (50.0 ± 5.7 g fish-1). Hemato-immune parameters were analyzed before and after the bacterial challenge. Red blood cell, hematocrit, hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and hydrogen peroxide (H2O2) and nitric oxide (NO) were evaluated. The MIC of the EEP was 13% (v/v) with a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Health; Hematology; Immunology; Oreochromis niloticus; Propolis; Stress. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000401785 |
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| NAKAGAKI,BRENDA N.; FREITAS-LOPES,MARIA A.; CARVALHO,ÉRIKA; CARVALHO-GONTIJO,RAQUEL; CASTRO-OLIVEIRA,HORTÊNCIA M.; REZENDE,RAFAEL M.; CARA,DENISE C.; SANTOS,MÔNICA M.; LOPES,RODRIGO PESTANA; DAVID,BRUNA A.; MENEZES,GUSTAVO B.. |
| ABSTRACT Resident and circulating immune cells have been extensively studied due to their almost ubiquitous role in cell biology. Despite their classification under the “immune cell department”, it is becoming increasingly clear that these cells are involved in many different non-immune related phenomena, including fetus development, vascular formation, memory, social behavior and many other phenotypes. There is a huge potential in combining high-throughput assays - including flow cytometry and gene analysis - with in vivo imaging. This can improve our knowledge in both basic and clinical cell biology, and accessing the expression of markers that are relevant in the context of both homeostasis and disease conditions might be instrumental. Here we describe... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Intravital microscopy; Phagocytes; Liver immunology; Fluorescent markers; Hepatology; Gastroenterology; Immunology. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000200601 |
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| Alves,C.M.; Vasconcelos,A.C.; Martins,A.S.; del Puerto,H.L.; Santos,F.G.A.; Nunes,J.E.S.; Campos,P.P.; Moro,L.. |
| The thymic morphometry analysis was used for determining apoptosis and atrophy of the thymus of eight puppies inoculated with canine distemper virus (CDV). Three healthy dogs were used as negative controls. Sections, 5µm thick, were stained by HE and Shorr, and the latter were evaluated by morphometry. CDV nucleoprotein was detected by immunohistochemistry. Morphometric results confirmed lymphoid hypotrophy in CDV inoculated dog thymuses, more stroma, less parenchyma and higher apoptotic index/field than negative control (not inoculated) puppies. Apoptosis plays a role in the mechanism of thymus atrophy that develops in canine distemper. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Puppy; Apoptosis; Thymus; Canine distemper; Immunology; Virus; Immunosuppression. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000400004 |
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| Delgobo,Murilo; Paludo,Katia Sabrina; Fernandes,Daniel; Oliveira,Junior Garcia de; Ortolan,Gilberto Luiz; Favero,Giovani Marino. |
| Abstract The gut is the main organ that mediates the contact between antigens with our organism, controlling the immune response against environmental factors, such as microbiota and food. Innate lymphoid cells participate in the gut-associated lymphoid tissue (GALT) maturation during the prenatal and early postnatal periods. After birth, breast milk provides the essential elements for the continuity of development of this tissue, leading to structural changes and healthy microbiota installation. The microbiota participates in the organogenesis of the GALT, as in the formation of intestinal villi, stimulating the proliferation of stem cells and maintaining the integrity of epithelial barrier. Foods are also involved in maturation of the GALT, where the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immunology; Gut; Peripheral Tolerance. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100901 |
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| Silva,Bruno Correa da; Jatobá,Adolfo; Vieira,Felipe do Nascimento; Mouriño,José Luiz Pedreira; Bolívar,Norha; Seiffert,Walter Quadros; Martins,Mauricio Laterça. |
| The aim of this study was to evaluate the immune response of hybrid surubim vaccinated by intraperitoneal injection and by immersion against Aeromonas hydrophila. Vaccine was prepared with formalin-inactivated A. hydrophila. Forty eight fishes (47±9g) were distributed in 12 tanks (4 fish / tank) in the following treatments (4 tanks / treatment): unvaccinated fish, vaccinated intraperitoneally and vaccinated by immersion. After 21 days, intraperitoneally vaccinated fishes showed the highest values of total protein and immunoglobulins, agglutination titer and serum antimicrobial activity. Lysozyme concentration in the serum was higher in the fishes vaccinated by immersion than unvaccinated fishes. Intraperitoneal vaccination induced the highest immune... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pseudoplatystoma; Aeromonas hydrophila; Vaccine; Immunology. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000100010 |
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| Cunha-Neto,E.; Rizzo,L.V.; Albuquerque,F.; Abel,L.; Guilherme,L.; Bocchi,E.; Bacal,F.; Carrara,D.; Ianni,B.; Mady,C.; Kalil,J.. |
| The hallmark of chronic Chagas' disease cardiomyopathy (CCC) is the finding of a T cell-rich inflammatory mononuclear cell infiltrate in the presence of extremely few parasites in the heart lesions. The scarcity of parasites in affected heart tissue casts doubt on the direct participation of Trypanosoma cruzi in CCC heart tissue lesions, and suggests the possible involvement of autoimmunity. The cells in the infiltrate are presumably the ultimate effectors of tissue damage, and there is evidence that such cells recognize cardiac myosin in molecular mimicry with T. cruzi proteins rather than primary reactivity to T. cruzi antigens (Cunha-Neto et al. (1996) Journal of Clinical Investigation, 98: 1709-1712). Recently, we have studied heart-infiltrating T... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Trypanosoma cruzi; Chagas' disease cardiomyopathy; Immunology; Cytokines; Gamma-interferon. |
| Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000100018 |
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| Registros recuperados: 221 | |
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