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Registros recuperados: 25
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Evaluation of antiarthritic activity of ginkgolic acid against Freund’s adjuvant induced arthritic rat model BJPS
Zhang,Ziqiang; Wang,Xiaogang; Li,Pengshan; Bai,Minghua; Qi,Wenbing.
This study aimed to analyze the antiarthritic activity of ginkgolic acid against the Complete Freund’s Adjuvant (CFA)-induced arthritis in rats. Arthritis was induced through an intradermal injection of CFA (0.1 mL) at the right hind footpad of adult Wistar Albino rats. Ginkgolic acid was administered orally at doses of 25 mg/kg and 50 mg/kg, respectively, once daily via gavage for 25 days upon inducing arthritis. Indomethacin was administered orally at a dose of 3 mg/kg twice in a week which served as positive control group. The animals were sacrificed and subjected to biochemical and histopathological analysis upon completion of treatment. Ginkgolic acid was able to reverse the arthritic effect (p < 0.01) induced by CFA in a dose dependent manner....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ginkgolic acid; Complete Freund’s Adjuvant (CFA); Osteoarthritis; Antioxidant; Anti-inflammatory; Histopathology.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100617
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Anti-inflammatory activity and identification of the Verbena litoralis Kunth crude extract constituents BJPS
Lima,Rachel de; Brondani,Juliana Calil; Dornelles,Rafaela Castro; Lhamas,Cibele Lima; Faccin,Henrique; Silva,Carine Viana; Dalmora,Sérgio Luiz; Manfron,Melânia Palermo.
Verbena litoralis is a plant popularly known as “gervãozinho-do-campo” in Portuguese. It is traditionally used for stomach, liver and gallbladder problems, and as an anti-inflammatory and anthelmintic. The goal of this study was to determine the chemical composition of the crude extract obtained from the aerial parts of V. litoralis by Ultra High Performance Liquid chromatography coupled with Mass Spectrometry in Tandem (UHPLC-MS/MS); assess the anti-inflammatory activity of ethyl acetate fraction and of crude extract; and verify liver, kidney and pancreas damage. In this study, the chemical composition of the extract was identified via UHPLC/MS/MS, assessing the anti-inflammatory activity of the crude extract and the acetate fraction in an induction model...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Verbena litoralis; UHPLC/MS; Flavonoids; Anti-inflammatory.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100540
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The in vitro and in vivo investigation of biological activities and phenolic analysis of Helichrysum plicatum subsp. plicatum BJPS
Taşkın,Turgut; Gezmiş,Tuğba; Çam,Muhammet Emin; Taşkın,Duygu; Çelik,Berna Özbek; Şenkardeş,İsmail; Süzgeç-Selçuk,Sevda.
In Turkey, Helichrysum genus is represented by 26 taxa belonging to 20 species in Turkish flora of which 14 ones are endemic to Turkey. The aerial parts of Helichrysum plicatum subsp. plicatum are used kidney stones, kidney and stomach ailments. The extraction procedures and solvents are important step in processing of bioactive constituents from the plant materials. Therefore, the aim of this study was to evaluate in vitro antioxidant, antimicrobial, anti-urease, anticholinesterase and in vivo anti-inflammatory activities of Helichrysum plicatum subsp. plicatum different extracts. In addition, the phenolic characterization of the Soxhlet and maceration methanol extracts which showed significant antioxidant, anti-urease, antimicrobial, anti-inflammatory...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Helichrysum plicatum subsp; Plicatum; Anti-inflammatory; Anti-urease; Anticholinesterase; HPLC-DAD-MS.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100554
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Antioxidant and anti-inflammatory activities of winery wastes seeds of Vitis labrusca Ciência Rural
Scola,Gustavo; Kappel,Virginia Demarchi; Moreira,José Claudio Fonseca; Dal-Pizzol,Felipe; Salvador,Mirian.
There are many studies about the biological activities of Vitis vinifera grape seeds, which are rich in phenolic compounds, known by their several health beneficial effects. However, until now there is no data about biological activities of the seeds of V. labrusca, specie found in South and North America. Every year, the global wine production (around 260 million hL) generates about 19.5 million ton of wastes, which are usually discarded in the environment. The aim of this research was to evaluate the antioxidant and anti-inflammatory activities of aqueous extracts of seeds from wine wastes of Vitis labrusca (cv. 'Bordo' and 'Isabella'). Both extracts showed significant antioxidant and anti-inflammatory activities, which are positively correlated with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: V. labrusca; Winery wastes; Antioxidant; Anti-inflammatory.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782011000700020
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Systemic and neurotoxic effects of epidural meloxicam in rabbits Ciência Rural
Felipe,Gracineide da Costa; Henrique,Fernanda Vieira; Rego,Renato Otaviano do; Alves,Alane Pereira; Oliveira,Kalyne Danielly Silva de; Firmino,Millena de Oliveira; Medeiros,Lylian Karlla Gomes de; Silva,Gustavo de Assis; Batista,Luanna Figueirêdo; Dantas,Antônio Flávio Medeiros; Souza,Bonifácio Benicio de; Nóbrega Neto,Pedro Isidro da.
ABSTRACT: The aim of this study was to assess systemic and neurotoxic changes following an epidural administration of meloxicamin to rabbits. Twelve adult rabbits four males and eight females; average mass, 1.9 ± 0.1kg were randomly divided into two groups: a control group (GC), which received a single dose of 0.9% NaCl epidurally in a volume of 0.3mL kg-1and a meloxicam group (GM), which received 0.2mg kg-1 meloxicam epidurally along with 0.9% NaCl in a total volume of 0.3mL kg-1. Heart rate, respiratory rate, body temperature, and neurological abnormalities were assessed prior to administration of anesthesia (H0), 1, 2, 3, 6, 12, and 24h following epidural puncture (H1, H2, H3, H6, H12, and H24, respectively), and every 24h afterward for 10 days after...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anti-inflammatory; Leporids; Spinal cord; Neurotoxicity.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000500602
Registros recuperados: 25
Primeira ... 12 ... Última
 

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