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| Silva,Cristiane de Bona da; Guterres,Sílvia S.; Weisheimer,Vanessa; Schapoval,Elfrides E.S.. |
| Superficial mycoses of the skin are among the most common dermatological infections, and causative organisms include dermatophytic, yeasts, and non-dermatophytic filamentous fungi. The treatment is limited, for many reasons, and new drugs are necessary. Numerous essential oils have been tested for both in vitro and in vivo antifungal activity and some pose much potential as antifungal agents. By using disk diffusion assay, we evaluated the antifungal activity of lemongrass oil and citral against yeasts of Candida species (Candida albicans, C. glabrata, C. krusei, C. parapsilosis and C. tropicalis). This study showed that lemongrass oil and citral have a potent in vitro activity against Candida spp. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lemongrass oil; Citral; Antifungal activity; Candida spp. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100014 |
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| Souza,Lúcia Kioko Hasimoto e; Oliveira,Cecília Maria Alves de; Ferri,Pedro Henrique; Santos,Suzana Costa; Oliveira Júnior,Juldásio Galdino de; Miranda,André Thiago Borges; Lião,Luciano Morais; Silva,Maria do Rosário Rodrigues. |
| Ethanolic extracts from leaves of Hyptis ovalifolia, H. suaveolens, H. saxatilis, Hyptidendrum canum, Eugenia uniflora, E. dysenterica, Caryocar brasiliensis and Lafoensia pacari were investigated for their antifungal activity against dermatophytes. The most effective plants were H. ovalifolia and E. uniflora, while Trichophyton rubrum was the most sensitive among the four dermatophytes species evaluated. This study has demonstrated antifungal properties of Brazilian Cerrado plant extracts in "in vitro" assays. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dermatophytes; Antifungal activity; Plant extracts; Susceptibility tests. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822002000300012 |
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| Santos,Maximillan Leite; Magalhães,Chaiana Froés; Rosa,Marcelo Barcellos da; Santos,Daniel de Assis; Brasileiro,Beatriz Gonçalves; Carvalho,Leandro Machado de; Silva,Marcelo Barreto da; Zani,Carlos Leomar; Siqueira,Ezequias Pessoa de; Peres,Rodrigo Loreto; Andrade,Anderson Assunção. |
| The effects of different solvents and extraction techniques upon the phytochemical profile and anti-Trichophyton activity of extracts from Piper aduncum leaves were evaluated. Extract done by maceration method with ethanol has higher content of sesquiterpenes and antifungal activity. This extract may be useful as an alternative treatment for dermatophytosis. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antifungal activity; Piper aduncum L.; Dermatophytes; Trichophyton; Extraction techniques. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400035 |
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| Pan,Feng; Liu,Zheng-Qiong; Chen,Que; Xu,Ying-Wen; Hou,Kai; Wu,Wei. |
| Abstract The aim of this paper is to identify and investigate an endophytic fungus (strain 28) that was isolated from Houttuynia cordata Thunb, a famous and widely-used Traditional Chinese Medicine. Based on morphological methods and a phylogenetic analysis of ITS sequences, this strain was identified as Chaetomium globosum. An antifungal activity bioassay demonstrated that the crude ethyl acetate (EtOAc) extracts of strain 28 had a wide antifungal spectrum and strong antimicrobial activity, particularly against Exserohilum turcicum (Pass.) Leonard et Suggs, Botrytis cinerea persoon and Botrytis cinerea Pers. ex Fr. Furthermore, the fermentation conditions, extraction method and the heat stability of antifungal substances from strain 28 were also studied.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Endophytic fungi; Houttuynia cordata Thunb.; Chaetomium globosum; Antifungal activity; Process parameter. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000200480 |
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| Khosravi,A.R; Minooeianhaghighi,M.H; Shokri,H; Emami,S.A; Alavi,S.M; Asili,J. |
| The goals of this study were to evaluate the effectiveness of Cuminum cyminum, Ziziphora clinopodioides and Nigella sativa essential oils to inhibit the growth of Aspergillus fumigatus and A. flavus and to evoke ultrastructural changes. The fungi were cultured into RPMI 1640 media in the presence of oils at concentrations of 8, 6, 5, 4, 3, 2, 1.5, 1.25, 1, 0.75 and 0.5 mg/ml in broth microdilution and 2, 1.5, 1 and 0.5 mg/ml in broth macrodilution methods with shaking for 48 h at 28ºC. Conidial and mycelial samples exposed to 0.25, 0.5, 1, 1.5 and 2 mg essential oils/ml for 5 days in 2% yeast extract granulated plus 15% Saccharose media were processed for transmission electron microscopy (TEM). Based on broth dilution methods, C. cyminum and to a lesser... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antifungal activity; Essential oil; Cuminum cyminum; Ziziphora clinopodioides; Nigella sativa; Aspergillus. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000100027 |
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| Saxena,Seema; Uniyal,Veena; Bhatt,R.P.. |
| Piedra, is an asymptomatic fungal infection of the hair shaft, resulting in the formation of nodules of different hardness on the infected hair. The infection also known as Trichomycosis nodularis is a superficial fungal infection arising from the pathogen being restricted to the stratum corneum with little or no tissue reaction. The nodules are a concretion of hyphae and fruiting bodies of the fungus. Two varieties of Piedra may be seen, Black Piedra and White Piedra. The fungus Trichosporon ovoides is involved in the occurrence of both types of Piedras. The purpose of this study was to examine the effectiveness of selected essential oils for the control of growth of the fungus and to determine whether the antifungal effect was due to the major compounds... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Essential oils; Piedra hair infection; Antifungal activity. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000400016 |
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| Shentu,Xuping; Zhan,Xiaohuan; Ma,Zheng; Yu,Xiaoping; Zhang,Chuanxi. |
| The endophytic fungus strain 0248, isolated from garlic, was identified as Trichoderma brevicompactum based on morphological characteristics and the nucleotide sequences of ITS1-5.8SITS2 and tef1. The bioactive compound T2 was isolated from the culture extracts of this fungus by bioactivity-guided fractionation and identified as 4β-acetoxy-12,13-epoxy-Δ9-trichothecene (trichodermin) by spectral analysis and mass spectrometry. Trichodermin has a marked inhibitory activity on Rhizoctonia solani, with an EC50 of 0.25 µgmL-1. Strong inhibition by trichodermin was also found for Botrytis cinerea, with an EC50 of 2.02 µgmL-1. However, a relatively poor inhibitory effect was observed for trichodermin against Colletotrichum lindemuthianum (EC50 = 25.60 µgmL-1).... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Trichoderma brevicompactum; Garlic; Endophytic fungus; Trichodermin; Antifungal activity. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000100036 |
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| Caneschi,César Augusto; Almeida,Angelina Maria de; Martins,Francislene Juliana; Hyaric,Mireille Le; Oliveira,Manoel Marques Evangelista; Macedo,Gilson Costa; Almeida,Mauro Vieira de; Raposo,Nádia Rezende Barbosa. |
| Abstract Onychomycosis is a fungal infection of the nail caused by high densities of filamentous fungi and yeasts. Treatment for this illness is long-term, and recurrences are frequently detected. This study evaluated in vitro antifungal activities of 12 organic compounds derived from amino alcohols against standard fungal strains, such as Trichophyton rubrum CCT 5507 URM 1666, Trichophyton mentagrophytes ATCC 11481, and Candida albicans ATCC 10231. The antifungal compounds were synthesized from p-hydroxybenzaldehyde (4a-4f) and p-hydroxybenzoic acid (9a-9f). Minimum inhibitory concentrations and minimum fungicidal concentrations were determined according to Clinical and Laboratory Standards Institute protocols M38-A2, M27-A3, and M27-S4. The amine series... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amino alcohols; Amides; Lipophilicity; Antifungal activity; Onychomycosis. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000300476 |
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| Shi,Jun-Feng; Sun,Chang-Qing. |
| ABSTRACT Tomato is one of the most important vegetables in the world. Decay after harvest is a major issue in the development of tomato industry. Currently, the most effective method for controlling decay after harvest is storage of tomato at low temperature combined with usage of chemical bactericide; however, long-term usage of chemical bactericide not only causes pathogen resistance but also is harmful for human health and environment. Biocontrol method for the management of disease after tomato harvest has great practical significance. In this study, antagonistic bacterium B-6-1 strain was isolated from the surface of tomato and identified as Enterobacter cowanii based on morphological characteristics and physiological and biochemical features combined... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antagonistic bacterium; Antifungal activity; Identification; Tomato. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000400706 |
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| Johann,Susana; Mendes,Beatriz G; Missau,Fabiana C; Resende,Maria A. de; Pizzolatti,Moacir G. |
| Crude extracts and fractions of five species of Polygala - P. campestris, P. cyparissias, P. paniculata, P. pulchella and P. sabulosa - were investigated for their in vitro antifungal activity against opportunistic Candida species, Cryptococcus gattii and Sporothrix schenckii with bioautographic and microdilution assays. In the bioautographic assays, the major extracts were active against the fungi tested. In the minimal concentration inhibitory (MIC) assay, the hexane extract of P. paniculata and EtOAc fraction of P. sabulosa showed the best antifungal activity, with MIC values of 60 and 30 µg/mL, respectively, against C. tropicalis, C. gattii and S. schenckii. The compounds isolated from P. sabulosa prenyloxycoumarin and 1,2,3,4,5,6-hexanehexol displayed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Polygalaceae; Polygala species; Antifungal activity; Rutin; Α-spinasterol. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000300027 |
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| Anibal,Paula Cristina; Peixoto,Iza Teixeira Alves; Foglio,Mary Ann; Höfling,José Francisco. |
| Ethanolic crude extracts prepared from the arils and seeds, pericarp, peels and from the whole fruit of Punica granatum, known as pomegranate, had their antifungal activity tested against Candida spp. The ethanolic crude extracts were analyzed by Mass Spectrometry and yielded many compounds such as punicalagin and galladydilacton. The extracts from the pericarp and peel showed activity against Candida spp., with MICs of 125 µg/mL. The effect of pericarp and peel extracts upon the morphological and structure of C. albicans and C. krusei were examined by scanning and transmission electron microscopy, with the visualization of an irregular membrane and hyphae, formation of vacuoles and thickening of the cell wall. The data obtained revealed potential... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Punica granatum; Punicalagin; Antifungal activity; Candida spp.; Electron microscopy. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000300027 |
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| Registros recuperados: 44 | |
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