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Chemical composition, anti-Trypanosoma cruzi and cytotoxic activities of the essential oil from green fruits of Protium ovatum (BURSERACEAE) Rev. Bras. Frutic.
Estevam,Elisângela Barbosa Borges; Alves,Cássia Cristina Fernandes; Esperandim,Viviane Rodrigues; Cazal,Cristiane de Melo; Souza,Alex Fonseca; Miranda,Mayker Lazaro Dantas.
Abstract Chagas disease is a major neglected tropical disease caused by Trypanosoma cruzi. It has been treated with the antiparasitic drugs nifurtimox and benzonidazole, which cause several side effects. The market for natural products has considerably grown lately and the use of plants has become an alternative to the development of novel drugs to cure the disease. Therefore, this study aimed at describing the chemical analysis of the essential oil from green fruits of Protium ovatum and evaluating their trypanocidal and cytotoxic potential. The essential oil was obtained by Clevenger hydrodistillation whereas its chemical composition was determined by gas chromatography coupled to mass spectrometry (GC-MS). The major compounds found in the essential oil...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Protium ovatum; SS-myrcene; Fruits; Essential oil; Trypanosoma cruzi; Cytotoxic analysis.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452018000106001
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Crude glycerin combined with food additives in feeding beef cattle R. Bras. Zootec.
Almeida,Marco Túlio Costa; Ezequiel,Jane Maria Bertocco; Paschoaloto,Josimari Regina; Carvalho,Vanessa Barbosa de; Perez,Henrique Leal; Fávaro,Vanessa Ruiz; D´Aurea,André Pastori; Homem Junior,Antonio Carlos.
ABSTRACT The objective of this study was to evaluate the effects of adding crude glycerin with food additives (sodium monensin or essential oils) to the diets of beef cattle on feed intake, ruminal parameters, in vitro digestibility, and production of greenhouse gases. Five ruminally cannulated Nellore steers were randomly assigned in a 5×5 Latin square design. The treatments were: control, without crude glycerin and additives; with essential oils and without crude glycerin; with sodium monensin and without crude glycerin; with essential oils and crude glycerin; and with sodium monensin and crude glycerin. The addition of crude glycerin caused a reduction in dry matter (DM) intake, increase in vitro dry matter digestibility, and decrease in vitro crude...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Byproduct; Essential oil; Ruminal parameters; Sodium monensin.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982018000100616
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Organic systems in the growth and essential-oil production of the yarrow Rev. Ciênc. Agron.
Ferraz,Elza Oliveira; Bertolucci,Suzan Kelly Vilela; Pinto,José Eduardo Brasil Pereira; Braga,Andreísa Flores; Costa,Andressa Giovannini.
Fertilization of the soil with organic fertilizers has been gaining importance within the concept of sustainable crop production. This study aimed evaluates the effects of dosages of cattle and poultry manure on Achillea millefolium L. as regards the vegetative growth and the content and chemical composition of its essential oil. For the cattle manure fertilization the dosages evaluated were: 1) soil with no fertilizer; 2) soil + 3.0 kg m-2; 3) soil + 6.0 kg m-2; 4) soil + 9.0 kg m-2 and 5) soil + 12.0 kg m-2. For fertilization with poultry manure: 1) soil without fertilizer; 2) soil + 1.5 kg m-2; 3) soil + 3.0 kg m-2; 4) soil + 4.5 kg m-2 and 5) soil + 6.0 kg m-2. The experimental design was completely randomized, with four replications per treatment and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Achillea millefolium L.; Essential oil; Organic fertilizer; Soil fertily; Biomass.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902014000100014
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Chemical composition and acaricidal activity of the leaf and fruit essential oils of Protium heptaphyllum (Aubl.) Marchand (Burseraceae) Acta Amazonica
Pontes,Wendel José Teles; Oliveira,José Cândido Guerra de; Câmara,Cláudio Augusto Gomes da; Lopes,Adelmo C. H. R.; Gondim Júnior,Manoel Guedes Correia; Oliveira,José Vargas de; Barros,Reginaldo; Schwartz,Manfred Oswald Erwin.
Essential oils from leaves and fruits of Protiumheptaphyllum collected in Tamandaré beach Pernambuco/Brazil were analysed by GC/MS and tested for toxicity and repellent effect against the two spotted spider mite (Tetranychus urticae). The major constituent identified in the fruits was alpha-terpinene (47.6 %) whereas oil from leaf contained mainly sesquiterpenes such as 9-epi-caryophyllene (21.4 %), trans-isolongifolanone (10.7 %) and 14-hydroxi-9-epi-caryophyllene (16.7 %). The fruit oil was found to be more effective against the mite when compared to the leaf oil. Both showed mortality properties and oviposition deterrence in higher concentration (10 µl.l-1 air), but only the essential oil from fruits induced repellence on T. urticae.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Protium heptaphyllum; Essential oil; Tetranychus urticae; Acaricidal activity.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672007000100012
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Cytotoxic evaluation of essential oil from Zanthoxylum rhoifolium Lam. leaves Acta Amazonica
Silva,Saulo Luis da; Figueiredo,Patrícia Maria; Yano,Tomomasa.
Zanthoxylum rhoifolium Lam is a plant popularly used as antimicrobial, for malaria and inflammatory treatment. The essential oil of Z. rhoifolium was extracted and its cytotoxic effects against HeLa (human cervical carcinoma), A-549 (human lung carcinoma), HT-29 (human colon adenocarcinoma), Vero (monkey kidney) cell lines and mice macrophages were evaluated. Some of the terpenes of its essential oil (ß-caryophyllene, alpha-humulene, alpha -pinene, myrcene and linalool) were also tested to verify their possible influence in the oil cytotoxic activity. The results obtained permitted to confirm that the essential oil is cytotoxic against tumoral cells (CD50 = 82.3, 90.7 and 113.6 µg/ml for A-549, HeLa e HT-29 cell lines, respectively), while it did not show...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Zanthoxylum; Essential oil; Cytotoxicity; SS-caryophyllene; Alpha-humulene.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672007000200015
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Teor e composição química do óleo essencial de Melissa officinalis L. in vitro sob influência do meio de cultura - DOI: 10.4025/actasciagron.v31i2.765 Agronomy
Reis, Érika Soares; IFMG; Pinto, José Eduardo Brasil Pereira; UFLA; Rosado, Luciana Domiciano Silva; UFLA; Corrêa, Ricardo Monteiro; IFMG.
Com o objetivo de avaliar o efeito do meio de cultura no teor e composição química do óleo essencial de Melissa officinalis, foi realizado o presente trabalho, que avaliaram três concentrações do meio de cultura MS. O experimento foi implantado em delineamento inteiramente casualizado, com sete repetições, e cada repetição foi representada por uma amostra de 20 g de plântulas frescas. A extração do óleo foi realizada em aparelho de Clevenger modificado com duração de 1h e 30 min. e a análise química foi realizada por cromatografia gasosa. Observou-se que o teor e a composição química do óleo essencial de M. officinalis foram influenciados pela concentração de sais do meio MS. As plântulas que se desenvolveram nos meios MS e MS/4 apresentaram maior teor de...
Palavras-chave: 5.01.00.00-9 Agronomia Melissa officinalis; Planta medicinal; Óleo essencial; Cultura de tecidos Fitotecnia Melissa officinalis; Medicinal plant; Essential oil; Tissue culture.
Ano: 2009 URL: http://periodicos.uem.br/ojs/index.php/ActaSciAgron/article/view/765
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Produção de biomassa e teor de óleo essencial em função da idade e época de colheita em plantas de hortelã-japonesa - doi: 10.4025/actasciagron.v33i2.5698 Agronomy
Chagas, Jorge Henrique; Universidade Federal de Lavras; Pinto, Jose Eduardo Brasil Pereira; Universidade Federal de Lavras, Laboratório de Cultura de Tecidos e Plantas Medicinais.; Bertolucci, Suzan Kelly Vilela; Universidade Federal de Lavras; Santos, Fúlvia Maria do; Unviersidade Fderal de Lavras.
O presente estudo objetivou avaliar o efeito da época e da idade da planta na colheita na produção de biomassa seca e no teor percentual do óleo essencial e o tempo de armazenamento das plantas de Mentha arvensis L. Foram instalados dois experimentos. No primeiro, foi avaliado o efeito de três idades na colheita, 80, 100 e 120 dias após o transplantio, e três idades na segunda colheita, 60, 75 e 90 dias. O delineamento utilizado foi de blocos casualizados, com quatro repetições, em esquema fatorial 3 x 3. No segundo experimento, foram avaliadas três épocas de colheita: início de janeiro, final de março e início de junho. O material colhido foi seco em estufa a 37°C, calculada a biomassa seca da parte aérea, extraído o óleo essencial em aparelho de...
Palavras-chave: 5.01.00.00-9; 5.01.03.00-8 planta medicinal; Mentha arvensis L.; Óleo essencial; Colheita Fitotecnia medicinal plant; Mentha arvensis L.; Essential oil; Harvest.
Ano: 2011 URL: http://periodicos.uem.br/ojs/index.php/ActaSciAgron/article/view/5698
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Microbiological activity of caraway (Carum carvi L.) essential oil obtained from different origin - doi: 10.4025/actasciagron.v35i4.16900 Agronomy
Seidler-Łożykowska, Katarzyna; Institute of Natural Fibres and Medicinal Plants; Kędzia, Bogdan; Institute of Natural Fibres and Medicinal Plants; Karpińska, Elżbieta; Institute of Natural Fibres and Medicinal Plants; Bocianowski, Jan; Poznań University of Life Sciences.
Caraway is one of the most important medicinal plant cultivated in Poland. Caraway essential oil performs medium antimicrobial activity, although it inhibits growth of many bacteria and fungi. The aim of the study was to evaluate microbiological activity of caraway oil obtained from fruit originated from different genotypes and investigate the correlation between this activity and essential oil content and its main components content. In the experiments done in 2008 and 2009, essential oil of 20 selected caraway genotypes originated from: European botanical gardens (17), cultivar ‘Konczewicki’ and our own breeding strains (2) was tested. The Minimal Inhibitory Concentration (MIC) of oil, which inhibited standard bacterial strain was investigated. MIC value...
Tipo: Fieldwork; laboratory analysis Palavras-chave: Caraway; Carvone; Essential oil; Limonene; Microbiological activity.
Ano: 2013 URL: http://periodicos.uem.br/ojs/index.php/ActaSciAgron/article/view/16900
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Chemical diversity of accessions of the in vivo germplasm bank of Varronia curassavica (Jacq.) Agronomy
Queiroz, Túlio Barroso; Fonseca, Francine Souza Alves da; Mendes, Aretusa Daniela Resende; Azevedo, Alcinei Mistico; Martins, Ernane Ronie.
Varronia curassavica (Jacq.) is a shrub and perennial plant native to Brazil that has therapeutic, anti-inflammatory and cicatrizing properties. The objective of this work was to study the chemical diversity of the native populations of this species maintained in the in vivo germplasm bank from Montes Claros, Minas Gerais, Brazil. The essential oils of 10 accessions analyzed in triplicate were obtained by hydrodistillation. Fifty-five compounds were detected, 46 of which were identified by GC-MS analysis. Essential oil yield ranged from 0.1 (VC-9) to 1.22% (VC-3) among the studied accessions. Three groups were formed by cluster analysis. Group A presented lower relative abundance of the compounds α-humulene (1.4%) and β-caryophyllene (8.5%). Conversely, in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Essential oil; Medicinal plant; Chemotype; Α-humulene; Β-caryophyllene.
Ano: 2019 URL: http://periodicos.uem.br/ojs/index.php/ActaSciAgron/article/view/42726
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Toxicity Of The Essential Oil Of The Cytral Chemotype Of Lippia Alba (Mill.) N. E. Brown Acta Toxicol. Argent.
Olivero-Verbel,Jesús; Guerrero-Castilla,Angélica; Stashenko,Elena.
The essential oil (EO) of Lippia alba (Mill.) N. E. Brown (Verbenaceae) has been traditionally used to treat several diseases. In this study, the acute toxic effects of the citral chemotype of L. alba EO were evaluated in mice. Animals were treated via intraperitoneal receiving the L. alba essential oil at doses between 50 and 2500 mg/kg, and the control group received sesame oil (vehicle). The EO induced dose-dependent neurotoxic effects at doses greater than 1000 mg/kg, including decreased locomotion, motor skills and muscle strength, hypotonia, dyspnea, kyphosis and convulsions. The EO was lethal at a dose of 2500 mg/kg. Animals receiving 1000 mg/kg were euthanized at the end of the treatment period and their blood and livers were collected for...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Essential oil; Lippia alba; Neurological damage; Acute toxicity.
Ano: 2010 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-37432010000100003
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Optimization of Pressurized Liquid Extraction of Essential Oil from Citrus Sinesis Peels. CIGR Journal
Olabinjo, Oyebola Odunayo; Olabinjo, Oyebola Odunayo; Ogunlowo, Agboola Simeon; OLIVEIRA, Alessandra Lopes; KAMIMURA, Eliana Setsuko.
Optimization of extraction of essential oil from Citrus sinesis (sweet orange) peels by Pressurized Liquid Extraction (PLE) was performed using response surface methodology (RSM). In order to obtain the maximum yield of essential oil, a two-factor Central Composite Design (CCD) experiments were conducted using extraction variables; temperature 46 - 70 ᵒC and static extraction cycles time 30 - 60 min. Subsequently the total phenolic content and antioxidant property using DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)) of essential oil was evaluated. The Response Surface analysis gave 70 °C and 60 min static extraction cycle time as the optimal condition to achieve the maximum yield of essential oil,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sweet orange peels; PLE; Essential oil; Antioxidant..
Ano: 2020 URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/5541
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Effect of thin layer drying on quality parameters of betel leaf (Piper betle L.) CIGR Journal
Meena, Amit; Guha, Proshanta; Nandi, Sujosh.
Betel leaf or “Paan” is contemplated as “a neglected green gold of India” due to its nutritional, financial, medicinal, social and cultural values. However, surplus production of the leaves during the glut season and lack of adequate storage facilities compel the betel leaf growers to sell it at a through away price. Therefore, the current study was taken up to enhance the shelf life of the leaves by four different drying methods like shed drying, hot air oven drying, vacuum drying and freeze drying. Eight different thin layer drying models were studied and compared based on coefficient of determination (R2), root mean square error (RMSE) and chi square. The results showed that Page model was the best fitted model for hot air oven drying and vacuum drying...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Betel leaf; Drying techniques; Drying models; Essential oil; Sensory attributes.
Ano: 2021 URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/5668
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Assessment of natural vegetal extracts in the inhibition of Leuconostoc mesenteroides MSI Agriscientia (Córdoba)
Serra,M. A; Garnero,J. A; Nicolau,V. V; Andreatta,A. E.
The present study focuses on the assessment of natural vegetal extracts in the inhibition of bacteria altering Vienna sausages whose growth becomes evident in the vacuum packed product after two to three weeks of refrigerated storage causing packages to swell. The different natural extracts were obtained by means of steam stripping, microwave assisted extraction and ultrasound assisted extraction. Apart from these extracts, commercial essential oils, pure compounds present in the vegetal kingdom and solutions were also evaluated. For each of the extracts, microbial sensitivity tests were carried out in order to assess the inhibitory/bactericidal effect against Leuconostoc mesenteroides MS1. It has been found that the essential oils obtained from Citrus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Leuconostoc mesenteroides MS1; Antimicrobial; Essential oil; Inhibitor; Bactericide; Vienna sausage.
Ano: 2018 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-298X2018000100006
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Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour Anais da ABC (AABC)
MOREIRA,DAVYSON L.; SOUZA,PATRÍCIA O.; KAPLAN,MARIA AUXILIADORA C.; PEREIRA,NUNO A.; CARDOSO,GERALDO L.; GUIMARÃES,ELSIE F..
The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Piperaceae; Piper solmsianum; Essential oil; Sarisan; Psychopharmacologic effect.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004
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Effect of essential oil from Citrus aurantium in maternal reproductive outcome and fetal anomaly frequency in rats Anais da ABC (AABC)
Volpato,Gustavo T.; Francia-Farje,Luis A.D.; Damasceno,Débora C.; Oliveira,Renata V.; Hiruma-Lima,Clélia A.; Kempinas,Wilma G..
Citrus aurantium L., commonly known as bitter orange, is widely used in folk medicine, but there is little data in the literature about the effects on pregnancy. The aim of the present study was to evaluate the influence of essential oil obtained from fruits of Citrus aurantium on the maternal reproductive outcome and fetal anomaly incidence in rats. Pregnant Wistar rats were randomized into four groups (n minimum = 12 animals/group): G1 = control, G2 to G4 = treated with essential oil from C. aurantium at dose 125, 250 and 500 mg/kg, respectively. Rats were orally treated, by gavage, with plant essential oil or vehicle during pre-implantation and organogenic period (gestational day 0-14). On gestational day 20 the rats were anaesthetized and the gravid...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Citrus aurantium; Essential oil; Limonene; Malformation; Pregnancy; Reproductive outcome.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100407
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Essential oil from two populations of Echinodorus grandiflorus (Cham. & Schltdl.) Micheli (Chapéu de couro) Anais da ABC (AABC)
Pimenta,Daniel S.; Figueiredo,Maria Raquel; Kaplan,Maria Auxiliadora C..
Analysis by Gas Chromatography and Gas Chromatography/Mass Spectrometry of the essential oils obtained from leaves of Echinodorus grandiflorus ("Chapéu de couro") from two different populations (Big Leaves and Small Leaves), collected monthly between September 1998 and December 1999 revealed 17 components. Phytol was the major constituent for both populations. The main sesquiterpene representatives are (E)-caryophyllene, alpha-humulene and (E)-nerolidol.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Echinodorus grandiflorus; Alismataceae; Essential oil; Sesquiterpenes; Diterpenes.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652006000400002
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Essential oil of Mitracarpus frigidus as a potent source of bioactive compounds Anais da ABC (AABC)
Fabri,Rodrigo L.; Coimbra,Elaine S.; Almeida,Ana C.; Siqueira,Ezequias P.; Alves,Tânia M.A.; Zani,Carlos L.; Scio,Elita.
In our previous work (Fabri et al. 2009), we showed that different extracts of Mitracarpus frigidus had significant antibacterial, antifungal and leishmanicidal activities. In order to increase our knowledge about this species, this work assesses the chemical composition and the in vitro biological activity of its essential oil. Thus, the essential oil obtained by hydrodistillation of the aerial parts of M. frigidus was analyzed by GC/MS. Among several compounds detected, 11 were identified, being linalool and eugenol acetate the major components. The essential oil exhibited a moderate antibacterial effect against Staphyloccocus aureus, Bacillus cereus, Pseudomonas aeruginosa and Enterobacter cloacae (MIC 250 µg/mL). On the other hand, it showed a strong...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mitracarpus frigidus; Essential oil; Antimicrobial; Antileishmanial; Cytotoxicity.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000400021
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Scutia buxifolia Reissek essential oil: in vitro antioxidant and antimicrobial activities Anais da ABC (AABC)
BOLIGON,ALINE A.; PIANA,MARIANA; BRUM,THIELE F. DE; FROEDER,AMANDA L.F.; BELKE,BIANCA V.; SCHWANZ,THIAGO G.; MARIO,DÉBORA N.; ALVES,SYDNEY H.; ATHAYDE,MARGARETH L..
The volatile oil from the stem bark of Scutia buxifolia (Rhamnaceae) has been obtained by hydrodistillation and analyzed by GC-MS. Twenty-one components were identified representing 99.93 % of the total oil composition, spathulenol (35.87%), β-cubebene (17.26%), germacrene D (6.43%), linalool (5.19%), carvacrol (4.05%) were the main components of S. buxifolia essential oil. Antioxidant and antimicrobial properties of the essential oil were evaluated by free radical scavenging (DPPH) assay and micro broth dilution method, respectively. S. buxifolia essential oil presented interesting radical scavenging activity (IC50 = 15.03 ± 0.11 µg/mL). The antibacterial assay showed that S. buxifolia stem bark essential oil was moderately active against the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scutia buxifolia; Essential oil; Antioxidant; Antimicrobial.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000301463
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Chemical composition and evaluation of antileishmanial and cytotoxic activities of the essential oil from leaves of Cryptocarya aschersoniana Mez. (Lauraceae Juss.) Anais da ABC (AABC)
ANDRADE,PRISCILA M. DE; MELO,DAIANA C. DE; ALCOBA,ANA ELISA T.; FERREIRA JÚNIOR,WALNIR G.; PAGOTTI,MARIANA C.; MAGALHÃES,LIZANDRA G.; SANTOS,TAINÁ C.L. DOS; CROTTI,ANTÔNIO E.M.; ALVES,CASSIA C.F.; MIRANDA,MAYKER L.D..
Abstract Leishmaniasis is an endemic disease caused by protozoa of the genus Leishmania, which affects around two million people worldwide. One major drawback in the treatment of leishmaniasis is the emergence of resistance to current chemotherapeutics. Medicinal and aromatic plants constitute a major source of natural organic compounds. In this study, the leaf essential oil of Cryptocarya aschersoniana was obtained by hydrodistillation in a Clevenger-type apparatus, and the chemical composition was analyzed by GC-MS and GC-FID. The essential oil of these species was predominantly constituted by monoterpene hydrocarbons (48.8%). Limonene (42.3%), linalool (9.7%) and nerolidol (8.6%) were the main constituents in the oil of C. aschersoniana. The in vitro...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cryptocarya aschersoniana; Lauraceae; Essential oil; Leishmania amazonensis; Cytotoxic activity.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000602671
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In vitro antiparasitic activity and chemical composition of the essential oil from Protium ovatum leaves (Burceraceae) Anais da ABC (AABC)
ESTEVAM,ELISÂNGELA B.B.; DEUS,ISABELLA P.B. DE; SILVA,VANESSA P. DA; SILVA,ELIZABETH A.J. DA; ALVES,CASSIA C.F.; ALVES,JOSÉ MILTON; CAZAL,CRISTIANE M.; MAGALHÃES,LIZANDRA G.; PAGOTTI,MARIANA C.; ESPERANDIM,VIVIANE R.; SOUZA,ALEX F.; MIRANDA,MAYKER L.D..
ABSTRACT Leishmaniasis and trypanosomiasis are globally widespread parasitic diseases which have been responsible for high mortality rates. Since drugs available for their treatment are highly hepatotoxic, nephrotoxic and cardiotoxic, adherence to therapy has been affected. Thus, the search for new, more effective and safer drugs for the treatment of these diseases is necessary. Natural products have stood out as an alternative to searching for new bioactive molecules with therapeutic potential. In this study, the chemical composition and antiparasitic activity of the essential oil from Protium ovatum leaves against trypomastigote forms of Trypanosoma cruzi and the promastigote forms of Leishmania amazonensis were evaluated. The essential oil was promising...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Trypanosoma cruzi; Leishmania amazonensis; Essential oil; Protium ovatum; Parasitic diseases.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000603005
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