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Bivalve genomics ArchiMer
Saavedra, Carlos; Bachere, Evelyne.
Interest in bivalve genomics has emerged during the last decade, owing to the importance of these organisms in aquaculture and fisheries and to their role in marine environmental science. Knowledge of bivalve genome structure, function and evolution resulting from 20th century "single gene" approaches is limited, but genomic technologies are called to dramatically increase it. Research based on linkage maps, transcriptomics and proteomics is being carried out to study the genetic and molecular bases of traits of interest in bivalve farming industry, mainly disease susceptibility, tolerance to environmental stress, and growth. The Pacific oyster (Crassostrea gigas) is now the focus of an international genome-sequencing consortium. The use of bivalves in...
Tipo: Text Palavras-chave: Shellfish toxins; Feeding; Stress; Proteomics; Genomics; Bivalves.
Ano: 2006 URL: http://archimer.ifremer.fr/doc/2006/publication-1709.pdf
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Estimation of genetic parameters of feed conversion ratio based on individual phenotypes and genomic data in sea bass ArchiMer
Besson, Mathieu; Allal, Francois; Chatain, Beatrice; Vergnet, Alain; Clota, Frederic; Ferrari, Sebastien; Vandeputte, Marc.
We estimated genetic parameters of feed conversion ratio (FCR) and daily growth coefficient (DGC) using individual phenotypes measured in aquariums under a restricted feeding regime and genomic information on 2,722 SNP markers. The results showed a moderate heritability of both traits (0.26 for FCR and 0.41 for DGC) as well as close to unity negative genetic correlation between them. Thus, FCR of fish in aquariums could be improved by selecting fish for higher DGC. Nevertheless, these results must be taken with caution until we know whether individual FCR measured in aquariums also reflects the FCR of fish reared in groups.    
Tipo: Text Palavras-chave: Feed efficiency; Fish; Genomics.
Ano: 2018 URL: http://archimer.ifremer.fr/doc/00446/55756/57416.pdf
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Detection and evaluation of selection signatures in sheep PAB
Paim,Tiago do Prado; Ianella,Patrícia; Paiva,Samuel Rezende; Caetano,Alexandre Rodrigues; Pimentel,Concepta Margaret McManus.
Abstract: The recent development of genome-wide single nucleotide polymorphism (SNP) arrays made it possible to carry out several studies with different species. The selection process can increase or reduce allelic (or genic) frequencies at specific loci in the genome, besides dragging neighboring alleles in the chromosome. This way, genomic regions with increased frequencies of specific alleles are formed, caracterizing selection signatures or selective sweeps. The detection of these signatures is important to characterize genetic resources, as well as to identify genes or regions involved in the control and expression of important production and economic traits. Sheep are an important species for theses studies as they are dispersed worldwide and have...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ovis aries; Analysis software; Animal genetic resources; Genetic improvement; Genomics; Molecular genetics; SNP markers.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2018000500527
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Validation of a customized subset of SNPs for sheep breed assignment in Brazil PAB
Paim,Tiago do Prado; McManus,Concepta; Vieira,Fábio Danilo; Oliveira,Stanley Robson de Medeiros; Facó,Olivardo; Azevedo,Hymerson Costa; Araújo,Adriana Mello de; Moraes,José Carlos Ferrugem; Yamagishi,Michel Eduardo Beleza; Carneiro,Paulo Luiz Souza; Caetano,Alexandre Rodrigues; Paiva,Samuel Rezende.
Abstract: The objective of this work was to evaluate the usefulness of a subset of 18 single nucleotide polymorphisms (SNPs) for breed identification of Brazilian Crioula, Morada Nova (MN), and Santa Inês (SI) sheep. Data of 588 animals were analyzed with the Structure software. Assignments higher than 90% confidence were observed in 82% of the studied samples. Most of the low-value assignments were observed in MN and SI breeds. Therefore, although there is a high reliability in this subset of 18 SNPs, it is not enough for an unequivocal assignment of the studied breeds, mainly of hair breeds. A more precise panel still needs to be developed for the widespread use in breed assignment.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ovis aries; Animal genetic resources; Certification of origin; Genomics; Traceability.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2019000104302
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Accuracy of genomic selection predictions for hip height in Brahman cattle using different relationship matrices PAB
Farah,Michel Marques; Fortes,Marina Rufino Salinas; Kelly,Matthew; Porto-Neto,Laercio Ribeiro; Meira,Camila Tangari; Carreño,Luis Orlando Duitama; Fonseca,Ricardo da; Moore,Stephen Stewart.
Abstract: The objective of this work was to evaluate the effects of genomic information on the genetic evaluation of hip height in Brahman cattle using different matrices built from genomic and pedigree data. Hip height measurements from 1,695 animals, genotyped with high-density SNP chip or imputed from 50 K high-density SNP chip, were used. The numerator relationship matrix (NRM) was compared with the H matrix, which incorporated the NRM and genomic relationship (G) matrix simultaneously. The genotypes were used to estimate three versions of G: observed allele frequency (HGOF), average minor allele frequency (HGMF), and frequency of 0.5 for all markers (HG50). For matrix comparisons, animal data were either used in full or divided into calibration (80%...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bos indicus; Beef cattle; Genomics; Rare alleles.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2018000600717
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Biomassza-alapú energiák innovációjának genomikai megközelítései AgEcon
Marothy, Gergely; Kondorosi, Eva; Bíró, Tibor.
A genomika valódi eszköz a biomassza-alapú energiák innovatív kutatása területén, egyes részterületei (metagenomika, transzkriptomika) ténylegesen alkalmazhatók a biomassza-alapanyag optimalizálása során, illetve a biomassza-konverzió hatékonyságának javításában, ezáltal a megújuló energiatípusok előállítási költségeinek csökkentésében. ------------------------------------------------ Genomics is a useful tool in innovative research into biomass energy. Certain fields of genomics (metagenomics, transcriptomics) have a practical application in biomass optimisation and in improving the efficiency of biomass, and can thus help reduce the costs of renewable energy production.
Tipo: Article Palavras-chave: Genomika; Biomassza; Kutatás; Innováció; Biomass energy; Genomics; Innovation; Research; Research and Development/Tech Change/Emerging Technologies.
Ano: 2011 URL: http://purl.umn.edu/119937
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Dietary histidine requirement of grow-out Nile tilapia (Oreochromis niloticus), based on growth performance, muscle development, expression of muscle-growth-related genes, and blood parameters R. Bras. Zootec.
Zaminhan-Hassemer,Micheli; Michelato,Mariana; Boscolo,Wilson Rogério; Urbich,Allan Vinnícius; Cruz,Thais Pereira da; Almeida,Fernanda Losi Alves de; Furuya,Valéria Rossetto Barriviera; Furuya,Wilson Massamitu.
ABSTRACT This research was conducted to determine optimal dietary histidine requirement of grow-out Nile tilapia, Oreochromis niloticus, based on muscle development, expression of muscle-growth-related genes, and blood parameters. Fish (n = 288, initial body weight of 64.17±0.53 g) were fed extruded diets with graded levels of histidine (4.23, 5.44, 7.17, 8.91, and 11.57 g kg−1), containing approximately 289 g kg−1 crude protein and 3565 kcal kg−1 digestible energy. The study followed a completely randomized design with five treatments and four replicates each, for 65 days. There was a quadratic effect of dietary histidine on final body weight, feed conversion, and net protein utilization, and the best values were optimized at 8.09, 7.88, and 7.33 g kg−1,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Amino acids; Aquaculture; Fish nutrition; Genomics.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982020000100201
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Genomic dissection of inbreeding depression: a gate to new opportunities R. Bras. Zootec.
Curik,Ino; Ferenčaković,Maja; Sölkner,Johann.
ABSTRACT Inbreeding depression, reduction in performance of quantitative traits, including reproduction and survival, caused by inbreeding, is a well-known phenomenon observed in almost all experimental, domesticated, and natural populations. In spite of its importance to the fate of a small population and numerous research performed in the last century, the genetic basis of inbreeding depression is still unclear. Recent fast development of molecular techniques has enabled estimation of a genomic inbreeding coefficient (FROH), which reflects realized autozygosity and can be further partitioned to chromosomes and chromosomal segments. In this review, we first describe classical approach used in the estimation of inbreeding in livestock populations, followed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Autozygosity; Detrimental load; Genomics; Runs of homozygosity.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982017000900773
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Assessment of the scientific-technological production in molecular biology in Brazil (1996-2007): the contribution of genomics programs Anais da ABC (AABC)
Meneghini,Rogério; Gamba,Estêvão C..
Several genome sequencing programs were launched in Brazil by the end of the nineties and the early 2000s.The most important initiatives were supported by the ONSA program (http://watson.fapesp.br/onsa/Genoma3.htm) and aimed at gaining domain in genomic technology and bringing molecular biology to the state of art. Two mainsets of data were collected in the 1996-2007 period to evaluate the results of these genome programs: the scientific production (Scopus and Web of Science databases) and the register of patents (US Patent and Trademark Office), both related to the progress of molecular biology along this period. In regard to the former, Brazil took a great leap in comparison to 17 other developed and developing countries, being only surpassed by China....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Science assessment; Genomics; Scientometrics; Molecular biology.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000200031
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Plant genomics: an overview Biol. Res.
CAMPOS-DE QUIROZ,HUGO.
Recent technological advancements have substantially expanded our ability to analyze and understand plant genomes and to reduce the gap existing between genotype and phenotype. The fast evolving field of genomics allows scientists to analyze thousand of genes in parallel, to understand the genetic architecture of plant genomes and also to isolate the genes responsible for mutations. Furthermore, whole genomes can now be sequenced. This review addresses these issues and also discusses ways to extract biological meaning from DNA data. Although genomic issuesare addressed from a plant perspective, this review provides insights into the genomic analyses of other organisms
Tipo: Journal article Palavras-chave: Genomics; Plant breeding; Gene discovery.
Ano: 2002 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300013
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Genomic Approaches in Marine Biodiversity and Aquaculture Biol. Res.
Huete-Pérez,Jorge A; Quezada,Fernando.
Recent advances in genomic and post-genomic technologies have now established the new standard in medical and biotechnological research. The introduction of next-generation sequencing, NGS,has resulted in the generation of thousands of genomes from all domains of life, including the genomes of complex uncultured microbial communities revealed through metagenomics. Although the application of genomics to marine biodiversity remains poorly developed overall, some noteworthy progress has been made in recent years. The genomes of various model marine organisms have been published and a few more are underway. In addition, the recent large-scale analysis of marine microbes, along with transcriptomic and proteomic approaches to the study of teleost fishes,...
Tipo: Journal article Palavras-chave: Aquaculture; Genomics; Marine biodiversity; Next-generation sequencing; Proteomics.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000400007
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Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses BJMBR
Scandalios,J.G..
Molecular oxygen (O2) is the premier biological electron acceptor that serves vital roles in fundamental cellular functions. However, with the beneficial properties of O2 comes the inadvertent formation of reactive oxygen species (ROS) such as superoxide (O2<FONT FACE=Symbol>·-</FONT>), hydrogen peroxide, and hydroxyl radical (OH<FONT FACE=Symbol>·</FONT>). If unabated, ROS pose a serious threat to or cause the death of aerobic cells. To minimize the damaging effects of ROS, aerobic organisms evolved non-enzymatic and enzymatic antioxidant defenses. The latter include catalases, peroxidases, superoxide dismutases, and glutathione S-transferases (GST). Cellular ROS-sensing mechanisms are not well understood, but a number of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Catalase; Aging; Telomeres; Gene regulation; Superoxide dismutase; Genomics.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700003
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A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences BJMBR
Mello-Coelho,V. de; Hess,K.L..
cDNA microarray is an innovative technology that facilitates the analysis of the expression of thousands of genes simultaneously. The utilization of this methodology, which is rapidly evolving, requires a combination of expertise from the biological, mathematical and statistical sciences. In this review, we attempt to provide an overview of the principles of cDNA microarray technology, the practical concerns of the analytical processing of the data obtained, the correlation of this methodology with other data analysis methods such as immunohistochemistry in tissue microarrays, and the cDNA microarray application in distinct areas of the basic and clinical sciences.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biotechnology; CDNA microarray; Gene expression; Genomics.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000011
Registros recuperados: 33
Primeira ... 12 ... Última
 

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